MULTIPLE BONDS BETWEEN MAIN-GROUP ELEMENTS AND TRANSITION-METALS .107. CATALYTIC-OXIDATION OF PARTIALLY AND FULLY FLUORINATED OLEFINS WITH OSMIUM-TETROXIDE
MULTIPLE BONDS BETWEEN MAIN-GROUP ELEMENTS AND TRANSITION-METALS .107. CATALYTIC-OXIDATION OF PARTIALLY AND FULLY FLUORINATED OLEFINS WITH OSMIUM-TETROXIDE
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DOI：
10.1002/anie.199213451
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发表时间：
1992-10-01
期刊：
影响因子：
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通讯作者：
SCHERER, W
中科院分区：
文献类型：
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作者：
HERRMANN, WA;EDER, SJ;SCHERER, W
一个普遍持有的概念最容易被修改。由于假设贫电子的烯烃不会与OsO4发生反应，所以从未用氟化烯测试过OsO4催化的烯烃顺式羟基化反应。但在标准反应条件下，即使是全氟烯烃也能快速、定量地转化为1，2，4，4，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，6，5，6，6，6，6，6，6，6，6，6，6，5，6，6，5，5，6-三甲氧基-1，4，4，4，4，4，4，4，4，4，4，4，4，6，6，6，6，4，4，4，4，4，4，4，4，4，4，4，4，4，4，4，4，4，它们随后的水解生成顺式二醇、酮或1，2-二酮。
A commonly held conception most be revised. The OsO4-catalyzed cis-hydroxylation of olefins was never tested with fluorinated olefins, because it was assumed the electron-poor olefins would not react with OsO4. But under the standard reaction conditions even perfluorinated olefins can be converted into osmate esters such as 1 quickly and quantitatively. Their subsequent hydrolysis provides cis-diols, ketones, or 1,2-diketones.