Head and neck lesions: Characterization with diffusion-weighted echo-planar MR imaging
Head and neck lesions: Characterization with diffusion-weighted echo-planar MR imaging
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DOI：
10.1148/radiol.2202010063
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发表时间：
2001-09-01
期刊：
影响因子：
19.7
通讯作者：
Ishiyama, T
中科院分区：
文献类型：
--
作者：
Wang, JC;Takashima, S;Ishiyama, T
目的：评价从扩散加权回波平面磁共振（MR）图像计算的表观扩散系数（adc）是否可以用于表征头颈部病变。材料与方法：对97例患者的97个头颈部病变，采用1.5 t MR对其进行弥散加权回波平面磁共振成像。图像的扩散加权因子b分别为0、500和1000 sec/mm(2)，并构建ADC图。计算病变、脑脊液和脊髓的adc。结果：81例（84%）患者获得可接受的ADC测量图像。恶性淋巴瘤的平均ADC为（0.66 +/- 0.17[SD]） × 10(-3) mm(2)/sec (n = 13)，显著小于癌（P < 0.001）。癌的平均ADC为（1.13 +/- 0.43）× 10(-3) mm(2)/sec (n = 36)，显著小于良性实体瘤（P = 0.002）。良性实体瘤的平均ADC为（1.56 +/- 0.51）× 10(-3) mm(2)/sec (n = 22)，显著小于良性囊性病变的平均值（2.05 +/- 0.62）× 10(-3) mm(2)/sec (n = 10) （P = 0.035）。脑脊液和脊髓的平均ADC在四组病变间无显著差异。当ADC小于1.22 X 10(-3) mm(2)/sec用于预测恶性肿瘤时，最高准确率为86%，灵敏度为84%，特异性为91%。结论：adc的测定可用于头颈部病变的表征。
PURPOSE: To evaluate whether apparent diffusion coefficients (ADCs) calculated from diffusion-weighted echo-planar magnetic resonance (MR) images can be used to characterize head and neck lesions.MATERIALS AND METHODS: Diffusion-weighted echo-planar MR imaging was performed with a 1.5-T MR unit in 97 head and neck lesions in 97 patients. Images were obtained with a diffusion-weighted factor, factor b, of 0, 500, and 1,000 sec/mm(2) and an ADC map was constructed. The ADCs of lesions, cerebrospinal fluid, and spinal cord were calculated.RESULTS: Acceptable images for ADC measurement were obtained in 81 (84%) patients. The mean ADC of malignant lymphomas, (0.66 +/- 0.17[SD]) X 10(-3) mm(2)/sec (n = 13), was significantly smaller (P < .001) than that of carcinomas. The mean ADC of carcinomas, (1.13 +/- 0.43) X 10(-3) mm(2)/sec (n = 36), was significantly smaller (P = .002) than that of benign solid tumors. The mean ADC of benign solid tumors, (1.56 +/- 0.51) X 10(-3) mm(2)/sec (n = 22), was significantly smaller (P = .035) than that of benign cystic lesions, (2.05 +/- 0.62) X 10(-3) mm(2)/sec (n = 10). No significant differences were seen in the mean ADC of cerebrospinal fluid and of spinal cord among four groups of lesions. When an ADC smaller than 1.22 X 10(-3) mm(2)/sec was used for predicting malignancy, the highest accuracy of 86%, with 84% sensitivity and 91% specificity, was obtained.CONCLUSION: Measurement of ADCs may be used to characterize head and neck lesions.