PseAAC-Builder: A cross-platform stand-alone program for generating various special Chou's pseudo-amino acid compositions

PseAAC-Builder: A cross-platform stand-alone program for generating various special Chou's pseudo-amino acid compositions
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DOI:
10.1016/j.ab.2012.03.015
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发表时间:
2012-06-15
影响因子:
2.9
通讯作者:
Gao, Yang
Gao, Yang
中科院分区:
生物学4区
文献类型:
--
作者:
Du, Pufeng;Wang, Xin;Gao, Yang

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伪氨基酸组成已被广泛用于将具有不同长度的复杂蛋白质序列转换为固定长度的数字特征向量,同时保留相当多的序列顺序信息。然而,到目前为止,公众可以使用的唯一软件是网络服务器PseAAC(http://www.csbio.sjtu.edu.cn/bioinf/PseAAC),该软件在处理大规模数据集方面存在一些局限性。在这里,我们提出了一个新的跨平台的独立的软件程序,称为PseAAC-Builder(http:www.pseb.sf.net),它可以用来生成各种模式的周的伪氨基酸组成在一个更有效和灵活的方式。预计PseAAC-Builder可能成为研究各种蛋白质属性的有用工具。(C)2012 Elsevier Inc. All rights reserved.
The pseudo-amino acid composition has been widely used to convert complicated protein sequences with various lengths to fixed length digital feature vectors while keeping considerable sequence order information. However, so far the only software available to the public is the web server PseAAC (http://www.csbio.sjtu.edu.cn/bioinf/PseAAC), which has some limitations in dealing with large-scale datasets. Here, we propose a new cross-platform stand-alone software program, called PseAAC-Builder (http://www.pseb.sf.net), which can be used to generate various modes of Chou's pseudo-amino acid composition in a much more efficient and flexible way. It is anticipated that PseAAC-Builder may become a useful tool for studying various protein attributes. (C) 2012 Elsevier Inc. All rights reserved.