Myocardial mechanics of percutaneous intramyocardial septal radiofrequency ablation

Myocardial mechanics of percutaneous intramyocardial septal radiofrequency ablation
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DOI:
10.1136/heartjnl-2022-321597
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发表时间:
2022-10-21
期刊:
影响因子:
5.7
通讯作者:
Liu, Liwen
Liu, Liwen
中科院分区:
医学1区
文献类型:
--
作者:
Li, Jing;Zhang, Juan;Liu, Liwen

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目的超声心动图引导下的经皮心肌内间隔射频消融术(PIMSRA,丽文手术)是肥厚型梗阻性心肌病(HOCM)的一种新的治疗选择。 PIMSRA对心肌力学的影响尚不清楚。方法2016年10月至2019年6月,对82例患者进行PIMSRA和三维散斑追踪超声心动图检查。在基线、术后立即和 1 年随访时完成超声心动图成像、定性和定量临床评估。结果 PIMSRA 后立即和 1 年随访时,左心室流出道 (LVOT) 峰值梯度显着降低(静息梯度:从 83.50 (61.25) 至 23.00 (41.75) mm Hg,p
Objective Echocardiography-guided Percutaneous IntraMyocardial Septal Radiofrequency Ablation (PIMSRA, Liwen procedure) is a novel treatment option for hypertrophic obstructive cardiomyopathy (HOCM). The impact of PIMSRA on myocardial mechanics is unknown.Methods Between October 2016 and June 2019, PIMSRA and 3-dimentional speckle tracking echocardiography were performed in 82 patients. Echocardiographic imaging, qualitative and quantitative clinical assessment were completed at baseline, immediately postprocedure and 1-year follow-up.Results There was a significant reduction in the peak left ventricular outflow tract (LVOT) gradients immediately following PIMSRA and at 1-year follow-up (resting gradients: from 83.50 (61.25) to 23.00 (41.75) mm Hg, p