NF-kappa B binds within a region required for B-cell-specific expression of major histocompatibility complex class II gene E alpha d.
NF-kappa B binds within a region required for B-cell-specific expression of major histocompatibility complex class II gene E alpha d.
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NF-kappa B 结合在 B 细胞特异性表达主要组织相容性复合体 II 类基因 E α d 所需的区域内。
DOI:
10.1128/mcb.9.2.844-846.1989
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发表时间:
1989
影响因子:
5.3
通讯作者:
Flavell,RA
中科院分区:
文献类型:
--
作者:
Blanar,MA;Burkly,LC;Flavell,RA
A region upstream of the murine major histocompatibility complex gene, Eαd, has been shown previously to be required for B-cell expression. Binding of the B-cell-specific factor, NF-κB, to a site within this region is indistinguishable from that observed with the kappa enhancer binding site. NF-κB may be responsible for EαdB-cell expression.