Scatter sensitive microscopic techniques to identify contrasting mucosal structures in ultrahigh-resolution optical coherence tomograms of mouse colon
Scatter sensitive microscopic techniques to identify contrasting mucosal structures in ultrahigh-resolution optical coherence tomograms of mouse colon
复制标题
散射敏感显微技术可识别小鼠结肠超高分辨率光学相干断层扫描中的对比粘膜结构
DOI：
10.1117/12.763968
复制
发表时间：
2008
期刊：
影响因子：
--
通讯作者：
J. Barton
中科院分区：
文献类型：
--
作者：
A. Tumlinson;L. Hariri;W. Drexler;J. Barton
Optical coherence tomography, optical coherence microscopy, reflectance confocal microscopy, and darkfield microscopy all derive contrast from the intensity of endogenous tissue scatter. We have imaged excised mouse colon tissue with these complimentary technologies to make conclusions about structural origins of scatter in the mouse colonic mucosa observed with endoscopic OCT. We find hyperintense scattering both from the cytoplasm of epithelial cells and from the boundary between epithelia and the lamina propria. We find almost no scatter from the portion of epithelial cells containing the nucleus. These observations substantiate explanations for the appearance of colonic crypts and the luminal surface.
影响因子：
3.8
作者：
Tumlinson, AR;Barton, JK;Drexler, W
通讯作者：
Drexler, W