DEVELOPMENT OF ORDER DURING CILIOGENESIS
DEVELOPMENT OF ORDER DURING CILIOGENESIS
复制标题
DOI：
10.1002/ar.1091620209
复制
发表时间：
1968-01-01
影响因子：
--
通讯作者：
FARBMAN, AI
中科院分区：
文献类型：
--
作者：
FRISCH, D;FARBMAN, AI
本文报道了15-18天小鼠胚胎鼻上皮纤毛发育的电子显微镜观察。可识别的纤毛一出现，纤毛微管对就出现了典型的9+2模式。然而，在这个阶段，没有观察到细胞内相邻纤毛的空间排列，这种排列由定向的中央微管反映在成虫身上。在同一阶段，分化的基足随机排列在同一细胞内相邻的基体上。这些发现的意义在于，观察到这些结构在协调的空间和时间关系中，在定向它们的力量之前是随机分化的，并且是独立的。
This report consists of an electron microscope study of developing cilia in nasal epithelium of 15–18 day mouse embryos. As soon as recognizable cilia were observed, the typical 9 + 2 pattern of ciliary microtubule pairs was present. However, at this stage the intracellular spatial alignment of adjacent cilia, reflected in the adult by directionally oriented central microtubules, was not observed. In the same stage, differentiated basal feet were randomly arranged on adjacent basal bodies within the same cell. The significance of these findings lies in the observation that the structures differentiate at random prior to and independent of the forces that orient them in a coordinated spatial and temporal relationship.