A quick and advantageous synthesis of 2H-1-benzopyran-2-ones unsubstituted on the pyranic nucleus
A quick and advantageous synthesis of 2H-1-benzopyran-2-ones unsubstituted on the pyranic nucleus
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DOI：
10.1055/s-2008-1067238
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发表时间：
2008-09-17
影响因子：
2.6
通讯作者：
Bratulescu, George
中科院分区：
文献类型：
--
作者：
Bratulescu, George
以苹果酸和苯酚为原料，在温和条件下合成了吡喃核上未取代的2 H-1-苯并吡喃-2-酮（香豆素）。该方法的优点是反应时间短、产率提高、产物纯度高、实验操作简单。
The synthesis of 2H-1-benzopyran-2-ones (coumarins) unsubstituted on the pyranic nucleus was realized by condensation of malic acid and phenols under mild conditions. A short reaction time, improved yields, good purity of the products, and an easy clean experimental protocol are the advantages of this procedure.