Preserved autoregulation in the rhesus spinal cord after high cervical cord section.
Preserved autoregulation in the rhesus spinal cord after high cervical cord section.
复制标题
高位颈髓切断后恒河猴脊髓保留了自动调节功能。
作者：
A. Kobrine;T. Doyle;N. Newby;H. Rizzoli
采用氢清除法测定猕猴脊髓局部血流量（SCBF），研究高位颈髓切断对脊髓自身调节现象的影响。在T7-11和C1-2进行椎板切除术。脊髓在C1-2完全切断。在正常碳酸条件下，然后在宽范围的血压（MAP）下测量胸脊髓中的SCBF。MAP或因出血而降低，或因静脉输注血管紧张素而升高。发现自动调节在50至125 mm Hg之间完好无损，其模式与在完整动物中观察到的模式相似。
The authors studied the effect of high cervical cord section on the phenomenon of autoregulation in the rhesus monkey with the hydrogen clearance method to measure focal spinal cord blood flow (SCBF). Laminectomies were performed at T7-11 and C1-2. The spinal cord was completely severed at C1-2. Under normocapnic conditions, SCBF was then measured in the thoracic spinal cord over a wide range of blood pressures (MAP). The MAP was either lowered by bleeding or raised by the intravenous infusion of angiotensin. Autoregulation was found to be intact between 50 and 125 mm Hg, following a pattern similar to the one observed in the intact animal.