Iodine-catalyzed allylation and propargylation of indoles with allylic and propargylic acetates
Iodine-catalyzed allylation and propargylation of indoles with allylic and propargylic acetates
复制标题
碘催化吲哚与烯丙基和炔丙基乙酸酯的烯丙基化和炔丙基化
DOI：
10.1016/j.tetlet.2007.04.044
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发表时间：
2007-06-04
影响因子：
1.8
通讯作者：
Chen, Yong-Jun
中科院分区：
文献类型：
--
作者：
Liu, Zhe;Liu, Li;Chen, Yong-Jun
发展了一种温和有效的吲哚烯丙基化/炔丙基化反应，具有高的区域选择性和优异的产率。在催化剂分子碘存在下，各种吲哚与烯丙基/炔丙基乙酸酯在室温下均能顺利反应，只生成C-3烷基化产物。(c)2007爱思唯尔有限公司保留所有权利。
A mild and efficient allylation/propargylation of indoles has been developed with high regioselectivity and excellent yields. In the presence of catalytic molecular iodine, various indoles could react with allylic/propargylic acetates smoothly at room temperature to exclusively provide C-3 alkylated products. (c) 2007 Elsevier Ltd. All rights reserved.