The value of combined cervical length measurement and fetal fibronectin testing to predict spontaneous preterm birth in asymptomatic high-risk women
The value of combined cervical length measurement and fetal fibronectin testing to predict spontaneous preterm birth in asymptomatic high-risk women
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DOI：
10.3109/14767058.2010.535872
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发表时间：
2011-07-01
影响因子：
1.8
通讯作者：
Shennan, Andrew H.
中科院分区：
文献类型：
--
作者：
Bolt, Lauren A.;Chandiramani, Manju;Shennan, Andrew H.
方法. 147名无症状的PTB高危妇女被转诊到专科产前诊所，并在12个月内接受CL和fFN检测。妇女在22 aEuroS 25 mm-HR 2.78，CL aEuroS < a千分之一货币符号25 mm-HR 3.14，p aEuroS < 0.05之间进行了两项测试。当CL结果与已知fFN相加时，风险比不显著。在高风险无症状女性中，fFN可用作主要筛查工具，CL测量保留用于具有阳性fFN结果的那些。需要进一步的前瞻性研究来证实我们的发现。
Methods. aEuro integral One hundred and forty-seven asymptomatic women at high-risk of PTB were referred to specialist antenatal clinics and underwent CL and fFN testing over a 12-month period. Women had both tests undertaken between 22 aEuroS25 mm-HR 2.78, CL aEuroS < a parts per thousand currency sign25 mm-HR 3.14, p aEuroS < 0.05). The hazard ratios were insignificant when CL results were added to a known fFN.Conclusions. aEuro integral In high-risk asymptomatic women, fFN may be used as a primary screening tool with CL measurement being reserved for those with a positive fFN result. Further prospective studies are needed to confirm our findings.