COMORBIDITY OF ALCOHOL AND ANXIETY DISORDERS AMONG COLLEGE-STUDENTS - EFFECTS OF GENDER AND FAMILY HISTORY OF ALCOHOLISM
COMORBIDITY OF ALCOHOL AND ANXIETY DISORDERS AMONG COLLEGE-STUDENTS - EFFECTS OF GENDER AND FAMILY HISTORY OF ALCOHOLISM
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DOI：
10.1016/0306-4603(93)90070-p
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发表时间：
1993-09-01
影响因子：
4.4
通讯作者：
SHER, KJ
中科院分区：
文献类型：
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作者：
KUSHNER, MG;SHER, KJ
我们在一个大的大学生样本(N=489)中评估了性别和酗酒家族史对焦虑症和酒精障碍(“共病”)共存的影响。一个结构化的诊断性访谈被用来引出焦虑症(29%)和酒精障碍(26%)的终生病史。在那些被诊断为焦虑症的人中，接受酒精诊断的受试者比例明显更高(9%比21%)。男性受试者，以及那些有酗酒父母病史的人，比其他受试者有明显更高的酒精障碍基准率。然而，这些因素并不影响与焦虑症的存在相关的酒精障碍风险的相对增加；也就是说，这些因素与(即适度的)共病风险没有交互作用。在讨论这些结果时，我们强调了在共病研究中识别和区分相互作用效应和基率效应的相关问题。
We evaluated the effects of gender and family history for alcoholism on the co-occurrence of anxiety disorders and alcohol disorders (''comorbidity'') in a large university student sample (N = 489). A structured diagnostic interview was used to elicit life-time histories of anxiety disorder (29%) and alcohol disorder (26%). The proportion of subjects receiving an alcohol diagnosis was significantly greater among those with an anxiety diagnosis (9% vs. 21%). Male subjects, as well as those with a parental history of alcoholism, had a significantly greater base-rate of alcohol disorder than did other subjects. However, these factors did not affect the relative increase in risk for an alcohol disorder associated with the presence of an anxiety disorder; that is, these factors did not interact with (i.e., moderate) comorbidity risk. In discussing these results, we emphasize issues relevant to identifying and distinguishing between interaction effects and base-rate effects in comorbidity studies.