Optimization of inclusive fitness
Optimization of inclusive fitness
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DOI：
10.1016/j.jtbi.2005.06.009
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发表时间：
2006-02-07
影响因子：
2
通讯作者：
Grafen, A
中科院分区：
文献类型：
--
作者：
Grafen, A
第一个完全明确的论点广泛支持了整个有机体生物学家的普遍信念，即自然选择往往会导致有机体表现出最大化其包容性适应性的行为。优化程序的使用可以清楚地说明这种信念应该被理解的含义，这与常见的数学假设形成鲜明对比，即它应该被形式化为某种李雅普诺夫函数甚至势函数。论证揭示了新的细节并揭示了潜在的假设。允许非常通用的遗传结构，并且存在任意的不确定性。然而，不允许适应度的频率依赖性。包容性适应性的逻辑立即将各种基因组内冲突汇集在一起，并引入了“p家族”的概念。因此，包容性适应性被纳入正式的达尔文主义项目中，该项目旨在将用于描述基因频率轨迹的运动数学（差分和微分方程）与用于描述目的和设计的优化数学联系起来。包容性健身的基本理论仍有重要问题需要回答。 (C) 2005 年，爱思唯尔有限公司出版。
The first fully explicit argument is given that broadly supports a widespread belief among whole-organism biologists that natural selection tends to lead to organisms acting as if maximizing their inclusive fitness. The use of optimization programs permits a clear statement of what this belief should be understood to mean, in contradistinction to the common mathematical presumption that it should be formalized as some kind of Lyapunov or even potential function. The argument reveals new details and uncovers latent assumptions. A very general genetic architecture is allowed, and there is arbitrary uncertainty. However, frequency dependence of fitnesses is not permitted. The logic of inclusive fitness immediately draws together various kinds of intra-genomic conflict, and the concept of 'p-family' is introduced. Inclusive fitness is thus incorporated into the formal Darwinism project, which aims to link the mathematics of motion (difference and differential equations) used to describe gene frequency trajectories with the mathematics of optimization used to describe purpose and design. Important questions remain to be answered in the fundamental theory of inclusive fitness. (C) 2005 Published by Elsevier Ltd.