Nickel-catalyzed reductive allylation of aryl bromides with allylic acetates
Nickel-catalyzed reductive allylation of aryl bromides with allylic acetates
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镍催化芳基溴与烯丙乙酸酯的还原烯丙基化
DOI：
10.1039/c3ob40232k
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发表时间：
2013-01-01
影响因子：
3.2
通讯作者：
Gong, Hegui
中科院分区：
文献类型：
--
作者：
Cui, Xiaozhan;Wang, Shulin;Gong, Hegui
本文重点介绍了镍催化的富电子芳基溴与各种取代的烯丙基碳酸酯的烯丙基化反应，使用锌作为末端还原剂，通过将芳基加成到较少受阻的烯丙基碳上，以良好到优异的产率区域选择性地提供E-烯烃。缺电子芳基溴化物和氯化物也是高效的偶联伴侣。
This paper highlights Ni-catalyzed allylation of electron-rich aryl bromides with a variety of substituted allylic carbonates using zinc as the terminal reductant, affording E-alkenes regioselectively in good to excellent yields by the addition of aryl to the less hindered allylic carbon. The electron-deficient aryl bromides and chlorides are also highly efficient coupling partners.