What is amniotic fluid ‘sludge’?
What is amniotic fluid ‘sludge’?
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什么是羊水“污泥”？
DOI：
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发表时间：
2007
影响因子：
7.1
通讯作者：
J. Costerton
中科院分区：
文献类型：
--
作者：
Roberto Romero;J. Kusanovic;J. Kusanovic;Jimmy Espinoza;Jimmy Espinoza;F. Gotsch;C. Nhan‐Chang;C. Nhan‐Chang;O. Erez;O. Erez;C. J. Kim;C. J. Kim;N. Khalek;P. Mittal;P. Mittal;Luís F. Gonçalves;Luís F. Gonçalves;Christoph Schaudinn;S. Hassan;S. Hassan;J. Costerton
羊水中存在自由漂浮的高回声物质，靠近子宫颈（图1（封面）和图22以及Videoclips S1和S2）先前已在有早产发作的女性1、有早产或先兆早产史的女性2以及妊娠中期有自发性早产风险的无症状女性3中进行了描述。我们提出术语羊水“污泥”来指这种超声检查结果，并提供证据表明，“污泥”是自发性早产和完整膜患者即将早产，组织学绒毛膜炎和羊膜腔微生物入侵的独立危险因素1。此外，羊水“污泥”已被确定为无症状的妇女在妊娠中期有自发性早产的风险，也是早产胎膜早破（PROM）和自发性早产的独立风险因素3。为了确定羊水“污泥”的性质，在超声引导下收集的材料在显微镜下进行检查，并进行微生物研究。
图1
经阴道三维超声图像显示羊水“污泥”靠近宫颈。
图2
二维超声图像显示一个短宫颈和宫颈漏斗患者的羊水“污泥”。急性坏死性绒毛膜炎（图5a）和急性精索炎（图5b）。新生儿被送到了新生儿...
The presence of free-floating hyperechogenic material within the amniotic fluid in close proximity to the uterine cervix (Figures 1 (cover) and and22 and Videoclips S1 and S2) has been described previously in women with an episode of preterm labor1, in women with a history of preterm delivery or threatened preterm labor2, and in asymptomatic women at risk for spontaneous preterm delivery in the mid-trimester of pregnancy3. We have proposed the term amniotic fluid ‘sludge’ to refer to this sonographic finding and provided evidence that ‘sludge’ is an independent risk factor for impending preterm delivery, histological chorioamnionitis and microbial invasion of the amniotic cavity in patients with spontaneous preterm labor and intact membranes1. Moreover, amniotic fluid ‘sludge’ has been identified in asymptomatic women at risk for spontaneous preterm delivery in the mid-trimester of pregnancy and is also an independent risk factor for preterm prelabor rupture of membranes (PROM) and spontaneous preterm delivery3. To determine the nature of amniotic fluid ‘sludge’, the material collected under sonographic guidance was examined under the microscope and microbiological studies were performed.
Figure 1
Rendered three-dimensional transvaginal ultrasound image demonstrating the presence of amniotic fluid ‘sludge’ in close proximity to the cervix.
Figure 2
Two-dimensional ultrasound image showing amniotic fluid ‘sludge’ in a patient with a short cervix and a cervical funnel. acute necrotizing chorioamnionitis (Figure 5a) and acute funisitis (Figure 5b). The newborn was admitted to the neonatal ...
影响因子：
120.7
作者：
Hall-Stoodley, Luanne;Hu, Fen Ze;Kerschner, Joseph E.
通讯作者：
Kerschner, Joseph E.
Dalkon Shield 尾部的扫描电子显微镜。
影响因子：
6.7
作者：
Bank,HL;Williamson,HO
通讯作者：
Williamson,HO