Effects of hypertension on attention, memory, and executive function in older adults
Effects of hypertension on attention, memory, and executive function in older adults
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DOI：
10.1037/0278-6133.22.6.587
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发表时间：
2003-11-01
影响因子：
4.2
通讯作者：
Ford, GA
中科院分区：
文献类型：
--
作者：
Saxby, BK;Harrington, F;Ford, GA
高血压与老年人认知功能障碍有关，但这些缺陷的性质和程度尚不清楚。简单的认知测量缺乏敏感性，而全面的评估产生了许多难以解释的变量。作者使用计算机化认知评估组合和执行功能的神经心理学测量对506名高血压和血压正常的老年参与者进行了主成分分析。复合因素评分用于重新分析223名未经治疗且无血管并发症的参与者的数据。高血压组在认知速度、情景记忆、工作记忆和执行功能方面存在缺陷，但在注意持续性方面无缺陷。使用综合评分简化了数据解释，并提示高血压对认知表现的差异性影响在个体测试结果中不明显。
Hypertension is associated with impairments in cognitive function in older adults, but the nature and extent of these deficits are unclear. Brief cognitive measures lack sensitivity, whereas comprehensive assessments produce numerous variables that are difficult to interpret. The authors performed a principal-components analysis using a computerized cognitive assessment battery and neuropsychological measures of executive function in 506 hypertensive and normotensive older participants. Composite factor scores were used to reanalyze data from 223 untreated participants without vascular complications. The hypertensive group had deficits in Speed of Cognition, Episodic and Working Memory, and Executive Function but not Continuity of Attention. Using composite scores simplified data interpretation and suggested differential effects of hypertension on cognitive performance not clearly evident in individual test results.