Methods in mammalian autophagy research.
Methods in mammalian autophagy research.
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DOI:
10.1016/j.cell.2010.01.028
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发表时间:
2010-02-05
期刊:
影响因子:
64.5
通讯作者:
Levine B
中科院分区:
文献类型:
--
作者:
Mizushima N;Yoshimori T;Levine B
Autophagy has been implicated in many physiological and pathological processes. Accordingly, there is a growing scientific need to accurately identify, quantify, and manipulate the process of autophagy in cells. However, as autophagy involves dynamic and complicated processes, it is often analyzed incorrectly. In this Primer, we discuss methods to monitor autophagy and to modulate autophagic activity, with a primary focus on mammalian macroautophagy.
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