Clearance of enteric Salmonella enterica serovar Typhimurium in chickens is independent of B-cell function

Clearance of enteric Salmonella enterica serovar Typhimurium in chickens is independent of B-cell function
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DOI:
10.1128/iai.74.2.1442-1444.2006
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发表时间:
2006-02-01
影响因子:
3.1
通讯作者:
Smith, AL
Smith, AL
中科院分区:
医学2区
文献类型:
--
作者:
Beal, RK;Powers, C;Smith, AL

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肠炎沙门氏菌血清型鼠伤寒沙门氏菌在鸡的肠道中定植,并在大约3周内从肠道中清除。感染诱导高水平的特异性抗体,但B细胞在原发性感染的清除或继发性感染后的增强清除中并不起重要作用。
Salmonella enterica serovar Typhimurium colonizes the gut of chickens and is cleared from the intestine within about 3 weeks. Infection induces high levels of specific antibody, but B cells do not play an essential role in clearance of primary infection or in the enhanced clearance after secondary challenge.