HINT: a database of annotated protein-protein interactions and their homologs.

HINT: a database of annotated protein-protein interactions and their homologs.
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DOI:
10.2142/biophysics.1.21
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发表时间:
2005-01-01
期刊:
Biophysics (Nagoya-shi, Japan)
影响因子:
--
通讯作者:
Nakamura, Haruki
Nakamura, Haruki
中科院分区:
其他
文献类型:
--
作者:
Patil, Ashwini;Nakamura, Haruki

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尽管目前网上有大量的蛋白质-蛋白质相互作用数据库,但缺乏识别和列出不同物种中类似相互作用的来源。同源相互作用(HINT)数据库是一个或多个物种中蛋白质-蛋白质相互作用及其同源物的集合。相互作用及其同源物用真核生物同源群(KOG)ID、InterPro结构域、基因本体(GO)术语和蛋白质数据库(PDB)结构进行注释。HINT作为一个交互式Web服务器可在http://helix.protein.osaka-u.ac.jp/hint/上获得。
Despite the abundance of protein-protein interaction databases currently available online, a source that identifies and lists similar interactions in different species is lacking. The Homologous Interactions (HINT) database is such a collection of protein-protein interactions and their homologs in one or more species. The interactions and their homologs are annotated with Eukaryotic Cluster of Orthologous Groups (KOG) IDs, InterPro domains, Gene Ontology (GO) terminology and Protein Data Bank (PDB) structures. HINT is available as an interactive Web server at http://helix.protein.osaka-u.ac.jp/hint/.