Facile Access to Versatile Polyaromatic Building Blocks: Selectively Protected Benzocyclobutenedione Derivatives via Regioselective [2+2] Cycloaddition of α‐Alkoxybenzyne and Ketene Silyl Acetal
Facile Access to Versatile Polyaromatic Building Blocks: Selectively Protected Benzocyclobutenedione Derivatives via Regioselective [2+2] Cycloaddition of α‐Alkoxybenzyne and Ketene Silyl Acetal
复制标题
轻松获得多功能聚芳烃结构单元：通过 α-烷氧基苯炔和烯酮甲硅烷基乙缩醛的区域选择性 [2+2] 环加成选择性保护苯并环丁烯二酮衍生物
DOI：
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发表时间：
2002
期刊：
影响因子：
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通讯作者：
Keisuke Suzuki
中科院分区：
文献类型：
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作者：
Toshiyuki Hamura;T. Hosoya;H. Yamaguchi;Yokusu Kuriyama;M. Tanabe;Makoto Miyamoto;Y. Yasui;Takashi Matsumoto;Keisuke Suzuki
通过α-烷氧基苯和烯酮硅基缩醛的区域选择性[2+2]环加成，形成了一种容易、分散的高氧苯并环丁烯衍生物。所述环加合物可转化为选择性保护的烷氧基苯并环丁烯二酮，这是合成多芳香族化合物的一类有吸引力的化合物。作为一种可能的应用，描述了对多芳香族化合物的豪瑟方法中磺酰基酞的区域异构体对的不同接触。
A facile, divergent access to highly oxygenated benzocyclobutene derivatives was developed via the regioselective [2+2] cycloaddition of α-alkoxybenzynes and ketene silyl acetals. The cycloadducts could be converted to selectively protected alkoxybenzocyclobutenediones, an attractive class of compounds for the synthesis of polyaromatic compounds. As one possible application, divergent access to a regioisomer pair of sulfonylphthalides for the Hauser approach to polyaromatic compounds is described.