[The risk factors analysis and optimal timing for drainage of lymphocele infection after pelvic lymphadenectomy in patients with endometrial cancer].
[The risk factors analysis and optimal timing for drainage of lymphocele infection after pelvic lymphadenectomy in patients with endometrial cancer].
复制标题
子宫内膜癌盆腔淋巴结清扫术后淋巴囊肿感染的危险因素分析及最佳引流时机
DOI：
10.3760/cma.j.issn.0376-2491.2017.23.002
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发表时间：
2017
影响因子：
--
通讯作者：
F. Xue
中科院分区：
文献类型：
--
作者：
M. Pan;Y. Wang;Y. Yan;Q. Wang;S. Jiang;C. Han;X. H. Zhang;F. Xue
目的：探讨盆腔淋巴结清扫术后淋巴囊肿感染的发生率、危险因素及最佳引流时机。方法：回顾性研究2009年1月至2016年4月在天津医科大学总医院收治的397例子宫内膜癌患者，其中76例出现淋巴囊肿，20例出现淋巴囊肿感染。结果：（1）淋巴囊肿感染发生率为5.04%（20/397）。单因素分析显示淋巴囊肿直径≥5 cm、术后贫血与淋巴囊肿形成相关（P<0.001，P=0.023）。多因素调整因素Logistic分析显示，淋巴囊肿直径≥5 cm是淋巴细胞感染的独立危险因素（P<0.001）。 (2)单纯抗生素治疗的病例总治疗时间往往短于抗生素联合引流治疗的病例(P=0.008)。然而，对于需要引流的严重病例，与第4天或之后开始的病例相比，第3天开始引流的总治疗时间显着缩短（P=0.048）。结论：明确淋巴囊肿感染的危险因素，采取有效措施，有利于降低淋巴囊肿感染的发生率。除抗生素外需引流时，越早引流，治疗周期越短。
Objcetive: To investigate the incidence and risk factors of Lymphocele infection and the optimal timing for drainage after pelvic lymphadenectomy. Methods: This retrospective study was carried out on 397 patients who received a pelvic lymphadenectomy with or without a para-aortic lymphadenectomy between January 2009 and April 2016, due to endometrial cancer in General hospital of Tianjin medical university.A total of 76 patients developed lymphocele and 20 patients developed lymphocele infection. Results: (1)The incidence of lymphocele infection was 5.04% (20/397). Single factor analysis indicated diameter of lymphocele ≥5 cm and postoperative anemia were associated with lymphocele formation (P<0.001, P=0.023). Multiple factors Logistic analysis through the adjustment of the factors showed diameter of lymphocele ≥5 cm was the independent risk factors for lymphocyst infection (P<0.001). (2)The total treatment period of cases treated only with antibiotics tended to be shorter than that of cases treated with combined antibiotics and drainage (P=0.008). However, for severe cases which needed drainage, initiating the drainage by day 3 significantly shortened the total treatment period compared with cases started on or after day 4 (P=0.048). Conclusion: To identify the risk factors of the lymphocele infection is useful to help reduce the incidence of them with effective measurement.When drainage is required in addition to antibiotics, the earlier the drainage is performed, the shorter the treatment period is.