EXPRESSION OF SALMONELLA-TYPHI AND ESCHERICHIA-COLI OMPC IS INFLUENCED DIFFERENTLY BY MEDIUM OSMOLARITY - DEPENDENCE ON ESCHERICHIA-COLI OMPR
EXPRESSION OF SALMONELLA-TYPHI AND ESCHERICHIA-COLI OMPC IS INFLUENCED DIFFERENTLY BY MEDIUM OSMOLARITY - DEPENDENCE ON ESCHERICHIA-COLI OMPR
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DOI：
10.1111/j.1365-2958.1991.tb01894.x
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发表时间：
1991-05-01
影响因子：
3.6
通讯作者：
CALVA, E
中科院分区：
文献类型：
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作者：
PUENTE, JL;VERDUGORODRIGUEZ, A;CALVA, E
当伤寒沙门氏菌在低（NB + 0%蔗糖）或高（NB + 20%蔗糖）渗透压的营养肉汤（NB）中生长时，OmpC（一种主要的外膜蛋白）高度表达。 这与大肠杆菌OmpC的表达形成对比，大肠杆菌OmpC的表达在低渗透压下被抑制，在高渗透压下被增强，如先前所述（货车Alphen和Lugtenberg，1977; Verhoef等人，1979; Kawaji等人，1979年）。 然而，S.伤寒OmpC依赖于E. coli OmpR转录激活因子。 这些研究结果表明，在两种细菌中的基因表达的调控机制之间的差异，虽然共同的效应器似乎是共享的。
OmpC, a major outer-membrane protein, is highly expressed when Salmonella typhi is grown in nutrient broth (NB) of either low (NB + 0% sucrose) or high (NB + 20% sucrose) osmolarity. This contrasts with the expression of Escherichia coli OmpC, which is inhibited in low osmolarity and enhanced in high osmolarity, as has been described previously (van Alphen and Lugtenberg, 1977; Verhoef et al., 1979; Kawaji et al., 1979). Nevertheless, expression of S. typhi OmpC is dependent on the E. coli OmpR transcriptional activator. These findings suggest differences between the mechanisms of osmoregulation of gene expression in both bacteria, although common effectors appear to be shared.