Carotid artery distensibility - A reliability study
Carotid artery distensibility - A reliability study
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DOI：
10.7863/jum.2007.26.9.1157
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发表时间：
2007-09-01
影响因子：
2.3
通讯作者：
Rundek, Tatjana
中科院分区：
文献类型：
--
作者：
Godia, Elisa Cuadrado;Madhok, Rishi;Rundek, Tatjana
目标。颈动脉扩张性(CD)是衡量颈动脉弹性的指标，已被引入为心血管疾病的危险因素。关于超声CD测量的重复性的信息有限。本研究的目的是评估超声测量颈总动脉(CCA)内径和CD衍生指标的读数间可靠性。方法：研究方法。两个独立的读取器(R1和R2)测量了118名受试者的B/M超声记录的右侧颈总动脉的收缩内径(SD)和舒张期内径(DD)。计算得到的CD指标(应变、弹性模数[E]、刚度[P]和CID)。计算读数与颈动脉内径的3型组内相关系数(ICC3，1)。结果。平均标准差R1为7.15+/-1.43 mm，R2为7.24+/-1.43 mm。平均DDS分别为6.71+/-1.36 mm和6.68+/-1.41 mm。R1和R2的SD和DD的平均差值分别为0.08+/-0.40 mm(配对t检验，P=0.04)和0.03+/-0.43 mm(配对t检验，P=0.46)，读者群间相关系数分别为0.96和0.95。我们观察到人口统计学与颈动脉内径显著相关，但与衍生的CD指标或危险因素无关。结论。结果表明，B/M型超声测量颈总动脉内径具有良好的重复性。然而，颈动脉内径的线性测量的微小变化可能会对动脉力学特性的估计产生很大影响，如应变和杨氏模数。标准的边界识别方法可能不够精确和可重复性，无法在临床环境中使用。
Objective. Carotid distensibility (CD) is a measure of carotid artery elasticity that has been introduced as a risk factor for cardiovascular disease. information regarding reproducibility of sonographic CD measures is limited. The objective of this study was to evaluate the inter-reader reliability of sonographic measurements of common carotid artery (CCA) diameters and derived metrics of CD. Methods. Two independent readers (R1 and R2) measured the systolic diameter (SD) and diastolic diameter (DD) for the right CCA from the B/M-mocle sonographic registrations among 118 subjects. The derived CD metrics (strain, elastic modulus [E], stiffness [P], and CID) were calculated. The inter-reader type 3 intraclass correlation coefficients (ICC3,1) for carotid diameters were calculated. Results. The mean SDs standard deviation were 7.15 +/- 1.43 mm for R1 and 7.24 +/- 1.43 mm for R2. The mean DDs were 6.71 +/- 1.36 mm for R1 and 6.68 +/- 1.41 mm for R2. The mean differences of SD and DD between R1 and R2 were 0.08 +/- 0.40 mm (paired t test, P =.04) and 0.03 +/- 0.43 mm (paired t test, P =.46), respectively Inter-reader type 3 intraclass correlation coefficients were 0.96 for SD and 0.95 for DD. We observed a significant association of demographics with carotid diameters but not with derived CD metrics or risk factors. Conclusions. Our results suggest good reproducibility of CCA diameters measured with B/Mmode sonography. However, very small changes in linear measurements of carotid diameters can have big effects on estimates of arterial mechanical properties such as strain and Young's modulus. The standard boundary identification methods may not be precise and reproducible enough for use in a clinical setting.