Vasopressin and the transmission of paternal behavior across generations in mated, cross-fostered Peromyscus mice
Vasopressin and the transmission of paternal behavior across generations in mated, cross-fostered Peromyscus mice
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DOI：
10.1037/0735-7044.117.3.455
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发表时间：
2003-06-01
影响因子：
1.9
通讯作者：
Marler, CA
中科院分区：
文献类型：
--
作者：
Bester-Meredith, JK;Marler, CA
精氨酸抗利尿激素（AVP）在父代行为向子代的非基因组转移中的作用在Peromyscus中进行了研究。雄性加利福尼亚小鼠（P. calfornicus）暴露于白足鼠（P. leucopus）养父母较少的检索显示较少的生物后代检索。相比之下，白足鼠被加利福尼亚鼠养父母和亲生父母取回幼鼠的次数相同，并且在取回幼鼠行为上没有变化。终纹床核的avp免疫反应染色可以预测父亲的行为，因为它与取回的次数呈正相关，并且与依偎、梳理和窝内时间的得分呈正相关。作者将AVP作为早期经历塑造成年父亲行为的可能机制进行了讨论。
The role of arginine vasopressin (AVP) in the nongenomic transfer of paternal behavior from fathers to offspring was examined in Peromyscus. Male California mice (P. calfornicus) exposed to fewer retrievals by white-footed mouse (P. leucopus) foster parents displayed fewer retrievals of biological offspring. In contrast, white-footed mice were retrieved equally rarely by California mouse foster parents and by biological parents and displayed no changes in pup retrieval behavior. AVP-immunoreactive staining in the bed nucleus of the stria terminalis may predict paternal behavior because it correlated positively with retrievals and with a score consisting of huddling, grooming, and time inside the nest. The authors discuss AVP as a possible mechanism by which early experience shapes adult paternal behavior.