Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers

Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers
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DOI:
10.1183/09031936.02.00023202
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发表时间:
2002-11-01
影响因子:
24.3
通讯作者:
Morkve, O
Morkve, O
中科院分区:
医学1区
文献类型:
--
作者:
Hardie, JA;Buist, AS;Morkve, O

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慢性阻塞性肺疾病全球倡议(GOLD)将1期慢性阻塞性肺疾病(COPD)定义为1秒用力呼气量/用力肺活量(FEV 1/FVC)% 80%。第2阶段定义为FEV 1/FVC> 70岁。在一个随机、定义明确的亚组中,208名目前无呼吸道疾病且无明显呼吸困难或心脏病/高血压伴呼吸困难的从不吸烟的受访者中,71名能够进行可接受的肺量测定。这些健康的老年从不吸烟者中,约35%的FEV 1/FVC%> 80岁,约50%的人被归类为COPD,约三分之一的人FEV 1> 80岁。
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has defined stage 1 chronic obstructive pulmonary disease (COPD) as forced expiratory volume in one second/forced vital capacity (FEV1/FVC)% 80%. Stage 2 has been defined as FEV1/FVC 70 yrs. In a random, well-defined subgroup of 208 never-smoker respondents with no current respiratory disease and significant dyspnoea or heart disease/hypertension complicated with dyspnoea, 71 were able to perform an acceptable spirometry. Approximately 35% of these healthy, elderly never-smokers had an FEV1/FVC% of 80 yrs similar to50% would be classified as having COPD and approximately one-third would have an FEV1 of