Respiratory symptoms, bronchitis and asthma in children of Central and Eastern Europe
Respiratory symptoms, bronchitis and asthma in children of Central and Eastern Europe
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DOI：
10.1183/09031936.02.00260802
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发表时间：
2002-10-01
影响因子：
24.3
通讯作者：
Brunekreef, B
中科院分区：
文献类型：
--
作者：
Leonardi, GS;Houthuijs, D;Brunekreef, B
多中心中欧空气污染与呼吸健康研究(CEAR)旨在使用标准化问卷测量中东欧六国(CEE)小学生的呼吸健康，以便在该地区内以及与其他欧洲国家进行比较。1996年，在保加利亚、捷克共和国、匈牙利、波兰、罗马尼亚和斯洛伐克的25个城市地区进行了一项横断面研究。21,743名7-11岁学龄儿童的家长完成了一份基于世界卫生组织和国际儿童哮喘和过敏研究项目的问卷调查，问题涉及咳嗽和喘息症状，以及医生的诊断。一生中支气管炎的患病率为55.9%，哮喘为3.9%，哮喘、痉挛或阻塞性支气管炎的患病率为12.3%。在中东欧国家，支气管炎的患病率高于西欧，哮喘的患病率似乎低于西欧。然而，如果哮喘被定义为哮喘或哮喘、痉挛或阻塞性支气管炎的诊断，那么其患病率与西欧相当，或更高。在该地区，大多数呼吸参数的国家内差异小于国家间差异。医生诊断的国与国之间的比较似乎取决于对哮喘定义的选择。这项研究报告了欧洲范围内呼吸道症状和诊断的患病率比较。东西方哮喘患病率的部分差异可能归因于诊断实践的差异。
The multicentre Central European Study of Air Pollution and Respiratory Health (CESAR) aimed to measure the respiratory health of schoolchildren using a standardised questionnaire in six countries of Central and Eastern Europe (CEE), allowing comparisons within this region and with other European countries.A cross-sectional study was conducted in 25 urban areas of Bulgaria, Czech Republic, Hungary, Poland, Romania, and Slovakia in 1996. Parents of 21,743 schoolchildren of age 7-11 yrs completed a questionnaire based on items from the World Health Organization and International Study of Asthma and Allergies in Childhood questions on cough and wheeze symptoms, as well as on diagnoses by doctors.Life-time prevalence of bronchitis was 55.9%, asthma 3.9%, and asthmatic, spastic or obstructive bronchitis 12.3%. In CEE countries the prevalence of bronchitis is higher and prevalence of asthma appears lower than in Western Europe. However, if asthma is defined as a diagnosis of either asthma or asthmatic, spastic or obstructive bronchitis, then its prevalence is comparable to Western Europe, or higher.In this region, within-country variation for most respiratory parameters is less than between-country variation. Between-country comparisons in doctors' diagnoses appear dependent on the choice of definition of asthma. Europe-wide comparisons in prevalence of respiratory symptoms and diagnosis are reported in this study. Some of the East-West difference in asthma prevalence may be attributable to differences in diagnostic practice.