Combination Extended Smoking Cessation Treatment Plus Home Visits for Smokers With Schizophrenia: A Randomized Controlled Trial
Combination Extended Smoking Cessation Treatment Plus Home Visits for Smokers With Schizophrenia: A Randomized Controlled Trial
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DOI：
10.1093/ntr/ntw190
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发表时间：
2017-01-01
影响因子：
4.7
通讯作者：
McCreary, Charles
中科院分区：
文献类型：
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作者：
Brody, Arthur L.;Zorick, Todd;McCreary, Charles
简介：大多数精神分裂症患者在其一生中被诊断为烟草依赖。减少这一人群吸烟负担的一个主要障碍是，与没有精神疾病的吸烟者相比，这些吸烟者在接受标准治疗时的戒烟率较低。我们试图确定，如果组合扩展治疗（COMBEXT）和家访（HV）将导致吸烟者精神分裂症的改善结局：方法：34名吸烟者精神分裂症完成COMB-EXT与HV，COMB-EXT没有HV，或治疗照常（TAU）（随机分配）。COMB-EXT包括团体认知行为治疗（CBT）、安非他酮、尼古丁贴片和尼古丁含片，在2周内开始，并持续26次每周访视。HV包括两周一次的家庭访问，评估二手烟（SHS）暴露和参与者和家庭环境中其他人的简短行为治疗。TAU由CBT组和一系列单一或联合药物治疗试验组成。结果：接受COMB-EXT治疗的精神分裂症吸烟者（有或没有HV）每天的吸烟量比接受TAU治疗的吸烟者减少得更多（均为P
Introduction: The majority of people with schizophrenia have a diagnosis of tobacco dependence during their lifetime. A major obstacle to reducing the burden of cigarette smoking in this population is that these smokers have lower quit rates when undergoing standard treatment compared to smokers with no mental illness. We sought to determine if combination extended treatment (COMBEXT) and home visits (HV) would lead to improved outcomes in smokers with schizophrenia.Methods: Thirty-four cigarette smokers with schizophrenia completed either COMB-EXT with HV, COMB-EXT without HV, or treatment as usual (TAU) (random assignment). COMB-EXT consisted of group cognitive-behavioral therapy (CBT), bupropion, nicotine patch, and nicotine lozenge, which were initiated within 2 weeks and continued for 26 weekly visits. HV consisted of biweekly visits to the home with assessment of secondhand smoke (SHS) exposure and brief behavioral therapy with participants and others in the home environment. TAU consisted of group CBT plus serial single or combination medication trials as per standard care.Results: Smokers with schizophrenia who received COMB-EXT (with or without HV) had greater reductions in cigarettes per day than those treated with TAU (both ps