Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study
Ultra-high-dose methylcobalamin in amyotrophic lateral sclerosis: a long-term phase II/III randomised controlled study
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DOI：
10.1136/jnnp-2018-319294
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发表时间：
2019-04-01
影响因子：
11
通讯作者：
Kuzuhara, Shigeki
中科院分区：
文献类型：
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作者：
Kaji, Ryuji;Imai, Takashi;Kuzuhara, Shigeki
目的 评价肌肉注射超高剂量甲钴胺治疗肌萎缩侧索硬化症 (ALS) 的疗效和安全性。方法 373 例 ALS 患者（El Escorial 确诊或疑似；实验室支持的疑似；持续时间
Objective To evaluate the efficacy and safety of intramuscular ultra-high-dose methylcobalamin in patients with amyotrophic lateral sclerosis (ALS).Methods 373 patients with ALS (El Escorial definite or probable; laboratory-supported probable; duration