A SiO2/pHEMA-Based Polymer-Infiltrated Ceramic Network Composite for Dental Restorative Materials
A SiO2/pHEMA-Based Polymer-Infiltrated Ceramic Network Composite for Dental Restorative Materials
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DOI：
10.3390/jcs6010017
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发表时间：
2022-01
影响因子：
3.3
通讯作者：
H. Ikeda;Yōhei Kawajiri;Minako Kibune Sodeyama;H. Yano;Y. Nagamatsu;C. Masaki;R. Hosokawa;H. Shimizu
中科院分区：
文献类型：
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作者：
H. Ikeda;Yōhei Kawajiri;Minako Kibune Sodeyama;H. Yano;Y. Nagamatsu;C. Masaki;R. Hosokawa;H. Shimizu
SiO_2-聚甲基丙烯酸羟乙酯(PHEMA)复合材料因其良好的生物相容性而被广泛应用于生物材料领域。然而，由于它们的力学性能较差，目前还没有被应用于牙齿修复材料。在本论文中，我们开发了一种新型的具有聚合物渗透网络(PICN)结构的SiO_2/PHEMA基复合材料，用于牙科修复材料。将二氧化硅纳米颗粒和聚乙烯醇粘结剂的混合物在950℃下烧结，制得了多孔的二氧化硅块体。将含有70wt%-HEMA/30wt%-乙二醇二甲基丙烯酸酯和过氧化苯甲酰引发剂的单体混合物渗透到多孔SiO_2嵌段中，热聚合制备了具有PICN结构的SiO_2/PHEMA基复合材料。根据其力学性能、表面自由能以及与牙科粘合剂的粘接性能对该复合材料进行了表征。其弯曲强度为112.5±18.7 Mpa，弯曲弹性模量为13.6±3.4 Gpa，维氏硬度为168.2±16.1，与人类牙齿相近。复合材料中极性组分的表面自由能为19.6±2.5mN/m，表明该复合材料具有与胶粘剂粘接的活性表面。在硅烷偶联剂的存在下，复合材料与胶粘剂粘合良好。SiO_2/PHEMA基复合材料是一种潜在的牙科修复材料。
SiO2-poly(2-hydroxyethyl methacrylate) (pHEMA)-based composites have been widely used as biomaterials owing to their biocompatibility. However, they have not yet been applied as tooth restorative materials because of their poor mechanical properties. In the present paper, we develop a novel SiO2/pHEMA-based composite with a polymer-infiltrated network (PICN) structure for use in dental restorative materials. A mixture of SiO2 nanoparticles and a poly(vinyl alcohol) binder was sintered at 950 °C to fabricate a porous SiO2 block. A monomer mixture containing 70 wt%-HEMA/30 wt%-ethylene glycol dimethacrylate and a benzoyl peroxide initiator was infiltrated into the porous SiO2 block and heat-polymerized to fabricate the SiO2/pHEMA-based composite with a PICN structure. The composite was characterized according to its mechanical properties, surface free energy, and bonding properties with a dental adhesive. The flexural strength was 112.5 ± 18.7 MPa, the flexural modulus was 13.6 ± 3.4 GPa, and the Vickers hardness was 168.2 ± 16.1, which are similar values to human teeth. The surface free energy of the polar component of the composite was 19.6 ± 2.5 mN/m, suggesting that this composite has an active surface for bonding with the adhesive. The composite bonded well to the adhesive, in the presence of a silane coupling agent. The SiO2/pHEMA-based composite was demonstrated to be a potential candidate for dental restorative materials.