Prevalence and incidence of interstitial cystitis in a managed care population
Prevalence and incidence of interstitial cystitis in a managed care population
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DOI：
10.1097/01.ju.0000146114.53828.82
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发表时间：
2005-01-01
影响因子：
6.6
通讯作者：
Calhoun, EA
中科院分区：
文献类型：
--
作者：
Clemens, JQ;Meenan, RT;Calhoun, EA
目的：我们计算了太平洋西北地区管理护理人群中医生诊断的间质性膀胱炎（IC）在男性和女性中的患病率和发病率。材料和方法：1998年1月至2002年5月对Kaiser Permanente Northwest （Portland, Oregon）数据库进行计算机检索。在25 - 80岁的患者中，IC的患病率是通过以下4种定义来计算的：1)被诊断为IC的患者，2)被诊断为IC的患者没有任何共识的IC排除标准，3)同时接受过膀胱镜检查的患者，4)专门接受过膀胱镜检查并伴有腹水膨胀的IC患者。1年后（2003年5月）进行了第二次数据库检索，以确定IC的事件病例。定义1的IC患病率为每10万名女性197例，每10万名男性41例；定义2的IC患病率为每10万名女性158例，每10万名男性28例；定义3的IC患病率为每10万名女性99例，每10万名男性19例；定义4的IC患病率为每10万名女性45例，每10万名男性8例。根据定义2,1年的IC发病率为每10万名女性21例，每10万名男性4例。每个估计的男女比例都是5:1。结论：女性和男性间质性膀胱炎的患病率和发病率明显高于先前公布的估计。男性在IC患者中所占的比例比以前认识到的要高。
Purpose: We calculated the prevalence and incidence of physician diagnosed interstitial cystitis (IC) in men and women in a managed care population in the Pacific Northwest.Materials and Methods: A computer search of the Kaiser Permanente Northwest (Portland, Oregon) database was performed for January 1998 to May 2002. The prevalence of IC in patients 25 to 80 years old was calculated using the 4 definitions of 1) patients assigned a diagnosis of IC, 2) patients assigned a diagnosis of IC without any of the consensus IC exclusion criteria, 3) patients who had also had undergone cystoscopy and 4) patients who had specifically undergone cystoscopy with hydrodistention for IC. A second database search was performed 1 year later (May 2003) to identify incident cases of IC.Results: The prevalence of IC was 197 per 100,000 women and 41 per 100,000 men for definition 1, 158 per 100,000 women and 28 per 100,000 men for definition 2, 99 per 100,000 women and 19 per 100,000 men for definition 3, and 45 per 100,000 women and 8 per 100,000 men for definition 4. Using definition 2 the 1-year incidence of IC was 21 per 100,000 women and 4 per 100,000 men. The female-to-male ratio for each estimate was 5:1.Conclusions: The prevalence and incidence of interstitial cystitis is significantly higher for women and men than previously published estimates. Men account for a higher proportion of patients with IC than has previously been recognized.