Intact Chemoreceptor-Based Biosensors: Extreme Sensitivity to Some Excitatory Amino Acids
Intact Chemoreceptor-Based Biosensors: Extreme Sensitivity to Some Excitatory Amino Acids
复制标题
基于完整化学感受器的生物传感器：对某些兴奋性氨基酸极其敏感
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
G. Rechnitz
中科院分区：
文献类型：
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作者：
R. Buch;G. Rechnitz
摘要 使用完整的基于化学感受器的生物传感器来检测属于兴奋性氨基酸组的一些化合物。该生物传感器对低至 10−15M 浓度的红藻氨酸和使君子酸做出响应，与传统的电位生物传感器相比，灵敏度提高了约 9 个数量级。此外，完整的基于化学感受器的生物传感器对以前用生物传感器未检测到的新型化合物作出反应。
Abstract An intact chemeoreceptor-based biosensor is used to detect some compounds belonging to the excitatory amino acid group. The biosensor responds to concentrations of kainic acid and quisqualic acid as low as 10−15M, representing an increase in sensitivity of approximately nine orders of magnitude over more traditional potentiometric biosensors. Moreover, the intact chemoreceptor-based biosensor responds to a new class of compounds not previously detected with a biosensor.