Salt Intake and Risk of Disaster Hypertension Among Evacuees in a Shelter After the Great East Japan Earthquake
Salt Intake and Risk of Disaster Hypertension Among Evacuees in a Shelter After the Great East Japan Earthquake
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DOI：
10.1161/hypertensionaha.119.12943
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发表时间：
2019-09-01
期刊：
影响因子：
8.3
通讯作者：
Kario, Kazuomi
中科院分区：
文献类型：
--
作者：
Hoshide, Satoshi;Nishizawa, Masafumi;Kario, Kazuomi
本研究调查了盐摄入量与灾难性高血压风险之间的关系。我们分析了2011年4月30日和5月5日东日本大地震后避难所避难者健康状况的调查数据。在完成基本健康状况调查表并接受医学检查的272名受试者中，158名（58%）患有灾难性高血压（收缩压≥ 140 mm Hg或舒张压≥ 90 mm Hg）。通过现场尿液评估的平均估计钠摄入量与灾难性高血压显著相关（每1 g/d的比值比，1.16; 95% CI，1.05-1.30）。当我们将盐敏感性高血压的高危因素定义为年龄较大时，（>= 65岁），肥胖（体重指数>= 25 kg/m2）、慢性肾脏疾病和糖尿病，估计的钠摄入量被发现是总组中灾难性高血压的危险因素（每1 g/d的比值比，1.27; 95%CI，1.12-1.43），甚至在灾难前没有高血压的组中（n=146;每1 g/d的比值比，1.46; 95%CI，1.19-1.79）。在不存在高血压的人群中，根据是否存在盐敏感性高血压的高风险，估计钠摄入量与灾难性高血压之间存在相互作用（P=0.03）。灾难性高血压增加了微量白蛋白尿的风险（比值比，3.00; 95%CI，1.71-5.26; P
This study investigated the association between salt intake and risk of disaster hypertension. We analyzed the data of surveys evaluating the health condition of evacuees in shelters after the Great East Japan Earthquake on April 30 and May 5, 2011. Among 272 subjects who completed the basic health condition questionnaire and underwent a medical examination, 158 (58%) had disaster hypertension (systolic blood pressure >= 140 mm Hg or diastolic blood pressure >= 90 mm Hg). Average estimated sodium intake assessed by spot urine was significantly associated with disaster hypertension (odds ratio per 1 g/d, 1.16; 95% CI, 1.05-1.30). When we defined the high risk factors for salt-sensitive hypertension as older age (>= 65 years), obesity (body mass index, >= 25 kg/m(2)), chronic kidney disease, and diabetes mellitus, estimated sodium intake was found to be a risk factor for disaster hypertension in the total group (odds ratio per 1 g/d, 1.27; 95% CI, 1.12-1.43) and even in the group without prevalent hypertension before disaster (n=146; odds ratio per 1 g/d, 1.46; 95% CI, 1.19-1.79). There was an interaction between estimated sodium intake and disaster hypertension according to the presence or absence of high risk of salt-sensitive hypertension in the group without prevalent hypertension (P=0.03). Disaster hypertension conferred a risk of microalbuminuria (odds ratio, 3.00; 95% CI, 1.71-5.26; P