Tee-ing up a New Follicular Lymphoma Classification System.

Tee-ing up a New Follicular Lymphoma Classification System.
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建立新的滤泡性淋巴瘤分类系统。

DOI:
10.1158/2643-3230.bcd-22-0090
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发表时间:
2022
影响因子:
11.2
通讯作者:
Melnick,AriM
Melnick,AriM
中科院分区:
--
文献类型:
--
作者:
Melnick,AriM

文献摘要

相似文献

在这一期的《血癌发现》中,Han和他的同事发现滤泡性淋巴瘤(FL)可以根据其t细胞亚群组成的临床和功能相关性分层为不同的类别。他们的研究结果进一步表明,将FL细胞MHCII表达与特定t细胞标记物配对可能是一种有用的诊断方法,可以选择患者进行特定的免疫治疗或免疫增强治疗,而不依赖于基因谱。参见Han等人的相关文章,第428页(4)。
In this issue ofBlood Cancer Discovery, Han and colleagues find that follicular lymphomas (FL) can be stratified into distinct classes with clinical and functional relevance based on their T-cell subset composition. Their findings further indicate that pairing of FL cell MHCII expression with specific T-cell markers may represent a useful diagnostic approach to select patients for particular immunotherapies or immune augmentation therapies independent of genetic profiling.See related article by Han et al., p. 428 (4).