Clinical Assessment of Early Tooth Demineralization Using Polarization Sensitive Optical Coherence Tomography
Clinical Assessment of Early Tooth Demineralization Using Polarization Sensitive Optical Coherence Tomography
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DOI：
10.1002/lsm.21013
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发表时间：
2010-12-01
影响因子：
2.4
通讯作者：
Fried, Daniel
中科院分区：
文献类型：
--
作者：
Louie, Tiffany;Lee, Chulsung;Fried, Daniel
简介：本研究的目的是测试的假设，偏振敏感光学相干断层扫描（PS-OCT）可以用来非破坏性测量和量化的严重程度，早期脱矿的釉质上的颊和咬合面和评估的抑制作用的氟化物清漆在vivo.Methods：一个分裂口设计被用来评估的影响，氟化物清漆抑制溶解20个测试科目。正畸带颊侧窗粘固在前磨牙上，并在咬合面上产生小切口，作为增强脱矿作用的菌斑保留部位。30天后取出带环，并在咬合和颊侧区域进行体内PS-OCT扫描。牙齿被提取，切片，并分析使用偏振光显微镜（PLM）和横向显微放射照相术（TMR）进行比较与PS-OCT images.Results：高对比度PS-OCT图像采集的咬合面和颊面在体内。在正常组和龋坏组的牙合面和颊面积分反射率（Δ R）差异有统计学意义（P < 0.05）。尽管TMR和PS-OCT测量的矿化损失（Delta Z）和Delta R在氟涂料处理的颊面上较小，但差异无统计学意义（P > 0.05）。结论：我们的结果表明PS-OCT可以在活体上非破坏性地测量颊面和隐面的早期釉质脱矿。激光外科医学42：738-745，2010年。(C)2010 Wiley-Liss，Inc.
Introduction: The aims of this study were to test the hypothesis that polarization sensitive-optical coherence tomography (PS-OCT) can be used to non-destructively measure and quantify the severity of the early demineralization of enamel on buccal and occlusal surfaces and assess the inhibitory effect of fluoride varnish in vivo.Methods: A split mouth design was used to assess the effects of fluoride varnish on inhibiting dissolution on 20 test subjects. Orthodontic bands with a buccal window were cemented on the premolars and small incisions were produced on occlusal surfaces to serve as sites for plaque retention for enhanced demineralization. Bands were removed after 30 days and PS-OCT scans were acquired in vivo of occlusal and buccal areas. Teeth were extracted, sectioned, and analyzed using polarized light microscopy (PLM) and transverse microradiography (TMR) for comparison with the PS-OCT images.Results: High contrast PS-OCT images were acquired of both occlusal and buccal surfaces in vivo. Both occlusal and buccal surfaces, showed a significant difference (P < 0.05) in the integrated reflectivity (Delta R) between the "sound" and "carious" enamelgroups. Although the mineralloss (Delta Z) and Delta R measured using TMR and PS-OCT were less for the fluoride varnish-treated buccal surfaces the difference was not statistically significant (P > 0.05).Conclusions: Our results indicate that PS-OCT can non-destructively measure early enamel demineralization on the buccal and occulsal surfaces in vivo. Lasers Surg. Med. 42:738-745, 2010. (C) 2010 Wiley-Liss, Inc.