Medicinal benefits of green tea:: Part I.: Review of noncancer health benefits

Medicinal benefits of green tea:: Part I.: Review of noncancer health benefits
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DOI:
10.1089/acm.2005.11.521
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发表时间:
2005-06-01
影响因子:
2.6
通讯作者:
Morré, DM
Morré, DM
中科院分区:
医学4区
文献类型:
--
作者:
Cooper, R;Morré, DJ;Morré, DM

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茶,以绿茶或红茶的形式,是世界上消费最广泛的饮料之一。茶叶提取物也可以作为膳食补充剂出售。然而,随着人们对茶的健康特性的日益关注和科学研究的显著增加,本文综述了绿茶和红茶的药用特性和非癌症健康益处的最新发现。第二部分对绿茶提取物的抗癌活性进行了综述。绿茶含有一组独特的儿茶素,在抗氧化、抗血管生成和抗增殖试验中具有生物活性,可能与预防和治疗各种形式的癌症有关。虽然主要的茶儿茶素表没食子儿茶素没食子酸酯(EGCG)的生物学特性及其抗肿瘤特性一直是人们关注的焦点,但茶叶还具有其他健康益处;一些原因是由于存在其他重要的成分。与绿茶和红茶的抗氧化特性无关的特性可能是茶的抗癌活性、改善心脏健康和动脉粥样硬化的原因。绿茶中的茶氨酸可能会起到缓解压力的作用。氧化儿茶素(红茶中的茶黄素)可以降低血液中的胆固醇水平。绿茶提取物与其他来源的多酚成分的协同作用越来越被认为对红茶和绿茶的药用价值具有潜在的重要意义。此外,由于被认为具有抗氧化剂和抗衰老的特性,茶现在正被用作局部制剂。这些方面的每一个方面都进行了调查。
Tea, in the form of green or black tea, is one of the most widely consumed beverages in the world. Extracts of tea leaves also are sold as dietary supplements. However, with the increasing interest in the health properties of tea and a significant rise in scientific investigation, this review covers recent findings on the medicinal properties and noncancer health benefits of both green and black tea. In Part II, a review of anticancer properties of green tea extracts is presented. Green tea contains a unique set of catechins that possess biological activity in antioxidant, anti-angiogenesis, and antiproliferative assays potentially relevant to the prevention and treatment of various forms of cancer. Although there has been much focus on the biological properties of the major tea catechin epigallocatechin gallate (EGCg) and its antitumor properties, tea offers other health benefits; some due to the presence of other important constituents. Characteristics unrelated to the antioxidant properties of green and black teas may be responsible for tea's anticancer activity and improvement in cardiac health and atherosclerosis. Theanine in green tea may play a role in reducing stress. Oxidized catechins (theaflavins in black tea) may reduce cholesterol levels in blood. Synergistic properties of green tea extracts with other sources of polyphenolic constituents are increasingly recognized as being potentially important to the medicinal benefits of black and green teas. Furthermore, due to presumed antioxidant and antiaging properties, tea is now finding its way into topical preparations. Each of these aspects is surveyed.