Clinical Importance of Incidentally Detected Hyperenhancing Liver Observations on Portal Venous Phase Computed Tomography in Patients Without Known Malignancy or Liver Disease.
Clinical Importance of Incidentally Detected Hyperenhancing Liver Observations on Portal Venous Phase Computed Tomography in Patients Without Known Malignancy or Liver Disease.
复制标题
DOI：
10.1097/rct.0000000000001154
复制
发表时间：
2021-07-01
影响因子：
1.3
通讯作者：
Loehfelm TW
中科院分区：
文献类型：
--
作者：
Corwin MT;DiGeronimo RT;Navarro SM;Fananapazir G;Wilson M;Loehfelm TW
目的：在无已知恶性肿瘤或肝病的患者门静脉期CT上偶然发现的高强化肝脏中，确定临床重要肿块的发生率。对门静脉期CT进行回顾性研究，以确定非癌症或肝病患者肝脏高强化的观察结果。观察结果分为同质性、血管瘤或异质性。参照标准为：病理检查2例，肝脏CT/MRI检查40例，门静脉期CT复查≥2年81例，≥复查5年。在形态均一的83例或血管瘤形态的110例中，没有临床重要的肿块。在37个(5.4%)形态不均的肿瘤中，有2个具有临床意义的肿块(1个肝细胞癌和1个肝腺瘤)。在无已知癌症或肝脏疾病的患者中，门静脉期CT表现为均匀或典型的血管瘤形态的偶然高强化肝脏表现很可能是良性的。
To determine the prevalence of clinically important masses among incidental hyper-enhancing liver observations on portal venous phase CT in patients without known malignancy or liver disease. Retrospective search of portal venous phase CTs to identify hyper-enhancing liver observations in patients without cancer or liver disease. Observations were assigned a morphology of homogeneous, hemangioma, or heterogeneous. The reference standard was pathology (n=2), liver protocol CT/MRI (n=40), follow-up portal venous phase CT for ≥ 2 years (n=81), or clinical follow-up for ≥ 5 years (n=107). There were no clinically important masses among 83 observations with homogeneous morphology or 110 with hemangioma morphology. There were 2 clinically important masses (1 HCC and 1 hepatic adenoma) among 37 (5.4%) heterogeneous morphology observations. Incidental hyper-enhancing liver observations on portal venous phase CT with homogeneous or typical hemangioma morphology in patients without known cancer or liver disease are highly likely benign.