Simultaneous estimation of controllable parameters in a living tissue during thermal therapy.
Simultaneous estimation of controllable parameters in a living tissue during thermal therapy.
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DOI：
10.1016/j.jtherbio.2014.07.008
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发表时间：
2014-10
影响因子：
2.7
通讯作者：
A. Jalali;M. Ayani;M. Baghban
中科院分区：
文献类型：
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作者：
A. Jalali;M. Ayani;M. Baghban
在热疗期间，控制沿着组织的温度分布可以产生治疗优势。这可以通过适当地操纵热疗中的有效参数来获得，例如外部热源和皮肤表面处的传热系数。在这项研究中，这些参数估计同时在皮肤组织中的任意温度分布。采用全隐式有限体积法求解正问题，得到温度场数据。该数据被用作同时估计外部热源和皮肤表面处的传热系数的附加信息。这两个参数都被认为是时间的函数，因为没有关于它们的函数形式的信息，所以这个问题被归类为函数估计方法。采用共轭梯度法作为反演方法。两个测试用例被认为是测量误差的影响进行评估。估算结果与实测值的比较证实了该方法的准确性。
During hyperthermia, controlling the temperature distribution along the tissue can cause remedial advantages. This can be obtained by proper manipulation of effective parameters in hyperthermia such as the external heat source and the heat transfer coefficient at the skin surface. In this study, these parameters are estimated simultaneously for an arbitrary temperature distribution in a skin tissue. The direct problem is solved by the fully implicit finite volume method to obtain the temperature data. This data is used as additional information to estimate the external heat source and the heat transfer coefficient at the skin surface simultaneously. Both of these parameters are considered as functions of time, and since no information exists about their functional form, the problem is classified as the function estimation approach. Conjugate gradient method is applied as an inverse method. Two test cases are considered and the effect of measurement errors is evaluated. The comparison of estimated results with measurements confirms the accuracy of this method.