Arsenic exposure and seafood intake in Korean adults
Arsenic exposure and seafood intake in Korean adults
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DOI：
10.1177/0960327116665673
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发表时间：
2017-05-01
影响因子：
2.8
通讯作者：
Park, J. D.
中科院分区：
文献类型：
--
作者：
Bae, H-S;Kang, I-G;Park, J. D.
砷（As）广泛分布于环境中，人类可从各种来源（如空气、水、土壤和食物）接触到As。本研究通过测量韩国成年人尿液中的总砷含量及其与韩国人喜爱的食物--海鲜消费量的关系来评估韩国成年人的砷暴露水平。研究对象为2077名成年人，年龄从19岁到83岁不等，按地区、性别和年龄分层进行概率抽样。所有受试者均未因职业接触砷。我们使用问卷调查收集了研究对象的人口统计学特征、生活方式和食物消耗量的信息，并进行了尿液采样。饮食进行了评估，在个人访谈中使用的24小时回忆法。使用电感耦合等离子体质谱法（PerkinElmer NEXION 300 S; Concord，安大略，加拿大）分析尿液中的总砷。尿液中总砷的几何平均浓度为97.6 μ g/L，男性（103.9 μ g/L）高于女性（93.0 μ g/L）。尿中总砷含量受性别、年龄、海鲜摄入量和地理位置的影响。在这项研究中，尿中总砷与鱼类和贝类的消费量呈正相关，主要是通过鱼类和贝类/谷物/香料的As摄入量来确定的。这些研究结果表明，海鲜消费可能是韩国成年人尿砷水平的主要贡献者。
Arsenic (As) is widely distributed in the environment, and humans can be exposed to As from various sources such as air, water, soil, and food. This study was performed to evaluate the As exposure levels in Korean adults by measuring total As in urine and its relation with the consumption of seafood, a favorite food in Korea. A total of 2077 adults were the study subjects; they ranged in age from 19 to 83, and they were recruited by probability sampling stratified by area, sex, and age. None of the subjects had been exposed to As occupationally. We collected information about the demographic characteristics, lifestyles, and food consumption of study subjects using a questionnaire and followed urine sampling. Diet was assessed in individual interviews using the 24-h recall method. Total As in urine was analyzed using inductively coupled plasma mass spectrometry (PerkinElmer NEXION 300S; Concord, Ontario, Canada). The geometric mean concentration of total As in urine was observed to be 97.6 mu g/L and was higher in males (103.9 mu g/L) than in females (93.0 mu g/L). Total As levels in urine were affected by sex, age, seafood intake, and geographic location. In this study, total As in urine was positively correlated with fish and shellfish consumption, and was mainly determined by As intake through fish and shellfish/grains/flavors. These findings suggest that seafood consumption might be a major contributor to urinary As levels in Korean adults.