Type III effectors xopN and avrBS2 contribute to the virulence of Xanthomonas oryzae pv. oryzicola strain GX01
Type III effectors xopN and avrBS2 contribute to the virulence of Xanthomonas oryzae pv. oryzicola strain GX01
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III 型效应子 xopN 和 avrBS2 有助于增强米黄单胞菌 pv 的毒力。
DOI：
10.1016/j.resmic.2019.10.002
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发表时间：
2020-03-01
影响因子：
2.6
通讯作者：
Huang, Sheng
中科院分区：
文献类型：
--
作者：
Liao, Zhou-Xiang;Li, Jian-Yuan;Huang, Sheng
米黄单胞菌。oryzicola （Xoc）依靠其III型分泌系统（T3SS）将III型分泌效应物（T3SEs）转运到宿主细胞中，包括转录激活物样效应物（TALEs）和非转录激活物样效应物（non-TALEs）。T3SEs可以通过操纵宿主细胞生理来促进Xoc的定植和增强毒力。我们在广西分离的Xoc菌株GX01中标记了25个编码非故事性的基因。通过对non-TALEs的系统诱变，我们发现xopN和avrBs2对Xoc GX01的毒力有显著贡献，而xopN对Xoc GX01的毒力贡献此前是未知的。(C) 2019巴斯德研究所。Elsevier Masson SAS出版。版权所有。
Xanthomonas oryzae pv. oryzicola (Xoc) depends on its type III secretion system (T3SS) to translocate type III secreted effectors (T3SEs), including transcription activator-like effectors (TALEs) and nontranscription activator-like effectors (non-TALEs), into host cells. T3SEs can promote the colonization of Xoc and contribute to virulence by manipulating host cell physiology. We annotated 25 genes encoding non-TALEs in Xoc strain GX01, an isolate from Guangxi in the South China's rice growing region. Through systematic mutagenesis of non-TALEs, we found that xopN, the virulence contribution of which was previously unknown for Xoc, significantly contributes to the virulence of Xoc GX01, as does avrBs2. (C) 2019 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.