Validation and Reproducibility of Aortic Pulse Wave Velocity as Assessed With Velocity-Encoded MRI
Validation and Reproducibility of Aortic Pulse Wave Velocity as Assessed With Velocity-Encoded MRI
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DOI：
10.1002/jmri.21886
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发表时间：
2009-09-01
影响因子：
4.4
通讯作者：
de Roos, Albert
中科院分区：
文献类型：
--
作者：
Grotenhuis, Heynric B.;Westenberg, Jos M.;de Roos, Albert
目的：验证磁共振成像（MRI）评估主动脉脉搏波速度（PWVMRI）与PWV确定从侵入性主动脉内压力测量（PWVINV），并测试测量的重复性通过MRI.Materials和方法：PWVMRI与PWVINV进行了比较，在18个非连续的病人安排导管的可疑冠心病。在10名健康志愿者中进行了PWVMRI的重复性测试，这些志愿者在一个场合进行了PWVMRI的重复性测试。对所有参与者进行速度编码MRI，以评估总主动脉（Ao（total））、近端主动脉（Ao（prox））和远端主动脉（Ao（dist））的PWVMRI。结果：结果表示为平均值+/- SD、Pearson相关系数（PCC）和组内相关性（ICC）。PWVMRI和PWVINV之间的Ao（总）一致性良好（6.5 +/- 1.1 m/s vs. 6.1 +/- 0.8 m/s; PCC = 0.53），Ao（近端）（6.5 +/- 1.3 m/s vs. 6.2 +/- 1.1 m/s：PCC = 0.69）和Ao（dist）（6.9 +/- 1.1 m/s vs. 6.1 +/- 1.0 m/s; PCC = 0.71）Aototal的PWVMRI再现性较高（4.3 +/- 0.5 m/s vs. 4.6 +/- 0.7 m/s; ICC = 0.90，P < 0.01），Ao（近端）（4.3 +/- 0.9 m/s vs. 4.7 +/- 1.0 m/s; ICC = 0.87，P < 0.01）和Ao（dist）（4.3 +/- 0.6 m/s vs. 4.4 +/- 0.8 m/s：ICC = 0.92，P < 0.01）。主动脉脉搏波速度的MRI评估显示与有创压力测量具有良好的一致性，并且可以以高再现性确定。
Purpose: To validate magnetic resonance imaging (MRI) assessment of aortic pulse wave velocity (PWVMRI) with PWV determined from invasive intra-aortic pressure measurements (PWVINV) and to test the reproducibility of the measurement by MRI.Materials and Methods: PWVMRI Was compared with PWVINV in 18 nonconsecutive patients scheduled for catheterization for suspected coronary artery disease. Reproducibility of PWVMRI was tested in 10 healthy volunteers who underwent repeated measurement of PWVMRI at a single occasion. Velocity-encoded MRI was performed on all participants to assess PWVMRI in the total aorta (Ao(total)), the proximal aorta (Ao(prox)), and the distal aorta (Ao(dist)).Results: The results are expressed as mean +/- SD, Pearson correlation coefficient (PCC), and intraclass correlation (ICC). Good agreement between PWVMRI and PWVINV was found for Ao(total) (6.5 +/- 1.1 m/s vs. 6.1 +/- 0.8 m/s; PCC = 0.53), Ao(prox) (6.5 +/- 1.3 m/s vs. 6.2 +/- 1.1 m/s: PCC = 0.69) and for Ao(dist) (6.9 +/- 1.1 m/s vs. 6.1 +/- 1.0 m/s; PCC = 0.71) Reproducibility Of PWVMRI was high for Aototal (4.3 +/- 0.5 m/s vs. 4.6 +/- 0.7 m/s; ICC = 0.90, P < 0.01), Ao(prox) (4.3 +/- 0.9 m/s vs. 4.7 +/- 1.0 m/s; ICC = 0.87, P < 0.01), and Ao(dist) (4.3 +/- 0.6 m/s vs. 4.4 +/- 0.8 m/s: ICC = 0.92, P < 0.01).Conclusion: MRI assessment of aortic pulse wave velocity shows good agreement with invasive pressure measurements and can be determined with high reproducibility.