Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis
Diagnostic efficacy of alveolar bone loss of the mandible for identifying postmenopausal women with femoral osteoporosis
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DOI：
10.1259/dmfr/28366679
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发表时间：
2007-01-01
影响因子：
3.3
通讯作者：
Tanimoto, K.
中科院分区：
文献类型：
--
作者：
Ishii, K.;Taguchi, A.;Tanimoto, K.
目的：下颌骨皮质宽度（MCW）在曲面断层片上的检测可能有助于识别绝经后妇女骨质疏松症。与MCW相比，在全景X线片上检测到的下颌骨牙槽骨丢失（ABL）是否是一种潜在的准确的骨质疏松症筛查工具，目前还知之甚少。本研究的目的是评估是否ABL的下颌骨的全景X线片是有用的识别股骨骨质疏松症的绝经后妇女相比，MCW。方法：三百五十四名日本绝经后妇女（平均年龄+/- SD，56.8 +/- 7.7岁）被招募本研究。采用双能X线骨密度仪测量股骨骨密度。结果：多元回归分析显示股骨BMD与MCW（P < 0.001）、体重（P <0.001）、年龄（P <0.001）和下颌骨ABL（P = 0.029;校正r（2）= 0.380）显著相关。识别股骨骨质疏松症的ROC曲线下面积（AUC）分别为0.609 [95%置信区间（0），0.523-0.696]（下颌骨ABL）和0.779（95% CI，0.713-0.844）（MCW）。AUC的ABL的下颌骨表示较低的accuracy.Conclusions：我们的研究结果表明，ABL的下颌骨全景X线片可能是没有用的，用于识别绝经后妇女股骨骨质疏松症相比，MCW。
Objectives: Mandibular cortical width (MCW) detected on panoramic radiographs may be useful for identifying postmenopausal women with osteoporosis. There is little known regarding whether alveolar bone loss (ABL) of the mandible detected on panoramic radiographs is a potentially accurate screening tool for osteoporosis in comparison with MCW. The purpose of this study was to evaluate whether ABL of the mandible on panoramic radiographs is useful for identifying femoral osteoporosis in postmenopausal women in comparison with MCW.Methods: Three hundred and fifty-four Japanese postmenopausal women (mean age +/- SD, 56.8 +/- 7.7 years) were recruited for this study. Femoral BMD was measured by dual energy X-ray absorptiometry. Panoramic radiographs were obtained to estimate ABL of the mandible and MCW.Results: A multiple regression analysis revealed that femoral BMD was significantly associated with MCW (P < 0.001), weight (P < 0.001), age (P < 0.001) and ABL of the mandible (P = 0.029; adjusted r(2) = 0.380). The area under the ROC curve (AUC) for identifying femoral osteoporosis was 0.609 [95% confidence interval (0), 0.523-0.696] for ABL of the mandible and 0.779 (95% CI, 0.713-0.844) for MCW, respectively. AUC for ABL of the mandible indicated less accuracy.Conclusions: Our results suggest that ABL of the mandible on panoramic radiographs may not be useful for identifying postmenopausal women with femoral osteoporosis in comparison with MCW.