Acute destruction of the hip joints and rapid resorption of femoral head in patients with rheumatoid arthritis
Acute destruction of the hip joints and rapid resorption of femoral head in patients with rheumatoid arthritis
复制标题
类风湿性关节炎患者髋关节的急性破坏和股骨头的快速吸收
DOI：
10.3109/s10165-006-0516-0
复制
发表时间：
2006
影响因子：
2.2
通讯作者：
T. Tomatsu
中科院分区：
文献类型：
--
作者：
K. Yoshino;S. Momohara;K. Ikari;K. Kawamura;T. Mochizuki;T. Iwamoto;Y. Niki;Seiji Saitou;T. Tomatsu
本文报告三例类风湿性关节炎（RA）患者，均表现为髋关节急性破坏及股骨头快速吸收。这种情况发生在不到6个月的时间内，与快速破坏性髋关节病非常相似。所有三名患者均为绝经后活动性类风湿关节炎妇女，一直服用类固醇。其中2例患者每天最大剂量服用泼尼松龙（PSL）超过20 mg，所有患者均对缓解疾病的抗风湿药物（DMARDs）耐药。除髋关节问题外，1例髋关节病变侧周围有巨大滑囊炎，1例多发性类风湿结节和皮肤梗死，1例对侧股骨头下病变伴不全性骨折。结果，所有患者均接受了全髋关节置换术。我们建议对持续严重髋关节疼痛的类风湿关节炎患者进行重复X线检查。
We report three rheumatoid arthritis (RA) cases with acute destruction of hip joint and rapid resorption of femoral head. The condition occurred in less than 6 months and closely resembled rapid destructive coxarthrosis. All three patients were postmenopausal women with active RA who had been taking steroids. Two of the patients were taking prednisolone (PSL) of over 20 mg as maximum dose per day, and all patients were resistant to disease-modifying anti-rheumatic drugs (DMARDs). Other than the problems of their hip joints, one had a giant bursitis around the pathological side of the hip joint, another had multiple rheumatoid nodules and skin infarction, and the other suffered from insufficiency fracture of the contralateral femoral subcapital lesion. As a result, all of them had total hip arthroplasty. We recommend taking repetitive radiographs for RA patients with continuing severe hip pain.