Steviol glycoside biosynthesis

Steviol glycoside biosynthesis
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DOI:
10.1016/j.phytochem.2007.02.010
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发表时间:
2007-07-01
期刊:
影响因子:
3.8
通讯作者:
Telmer, P. G.
Telmer, P. G.
中科院分区:
生物学2区
文献类型:
--
作者:
Brandle, J. E.;Telmer, P. G.

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甜菊醇糖苷以高浓度存在于多年生草本植物甜叶菊(Stevia rebaudiana)的叶子中,并且其强烈的甜味以及在甜叶菊叶组织中的高浓度使其成为超过100年的研究兴趣的主题。甜菊醇糖苷是二萜类化合物,其生物合成途径与赤霉酸形成共有四个步骤。基因组学和植物生物化学的融合导致了生物合成途径中各种酶的基因编码的快速阐明。目前正在对这些基因编码的酶进行功能鉴定。该途径中的第一个关键步骤是合成糖苷配基甜菊醇,并且在叶组织中发现的各种糖苷是由许多葡糖基转移酶对甜菊醇的加工产生的。皇冠版权所有(c)2007年出版的爱思唯尔有限公司保留所有权利。
Steviol glycosides are found in high concentrations in the leaves of the Paraguayan perennial herb Stevia rebaudiana and their intense sweetness, as well as high concentration in Stevia leaf tissue, has made them the subject of research interest for over 100 years. Steviol glycosides are diterpenoids whose biosynthetic pathways share four steps in common with gibberellic acid formation. The convergence of genomics and plant biochemistry has led to the rapid elucidation of the genes coding for the various enzymes in the biosynthetic pathway. Functional characterization of the enzymes coded for by those genes is on-going. The first committed step in the pathway is the synthesis of the aglycone steviol and the various glycosides found in the leaf tissue result from the elaboration of steviol by a number of glucosyltransferases. Crown Copyright (c) 2007 Published by Elsevier Ltd. All rights reserved.