[Antimicrobial resistance changes of carbapenem-resistant Enterobacteriaceae strains isolated from children].
[Antimicrobial resistance changes of carbapenem-resistant Enterobacteriaceae strains isolated from children].
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DOI：
10.3760/cma.j.issn.0578-1310.2018.12.005
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发表时间：
2018-12-02
期刊：
影响因子：
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通讯作者：
Meng, J H
中科院分区：
文献类型：
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作者：
Guo, Y;Hu, F P;Meng, J H
目的：了解2005~2017年中国细菌耐药监测网(CHINET)儿童患者分离的耐碳青霉烯类肠杆菌科(CRE)菌株的流行情况及耐药性变化。方法：采用纸片扩散法(KB法)和全自动药敏系统进行药敏试验。根据临床和实验室标准协会(CLSI)2017版标准对结果进行分析。结果：4481株CRE临床分离株中，儿童CRE总患病率为6.4%，其中新生儿期8.8%，婴儿期7.3%，幼儿3.8%，学龄前4.0%，学龄期4.7%，青春期7.4%。柠檬酸杆菌Cre的流行情况。在2005-2017年间保持稳定，其他细菌呈上升趋势，高于成年组(P
Objective: To investigate the prevalence and resistance changes of carbapenem-resistant Enterobacteriaceae (CRE) strains isolated from children patients of Chinese Bacterial Resistance Surveillance Network (CHINET) from 2005 to 2017. Methods: Antimicrobial susceptibility testing was carried out by disk diffusion method (KB method) and automated systems. Results were analyzed according to the Clinical and Laboratory Standards Institute (CLSI) 2017 edition standards. Results: Among the 4 481 CRE clinical strains, the overall prevalence of CRE in children was 6.4%, including 8.8% in neonatal period, 7.3% in infancy, 3.8% in early childhood, 4.0% in preschool, 4.7% at school age and 7.4% of puberty. The CRE prevalence of citrobacter spp. remained stable in 2005-2017, whereas other bacteria showed an upward trend, which was higher than that of the adult group (P