Temporal Trends in Survival to Adulthood Among Patients Born With Congenital Heart Disease From 1970 to 1992 in Belgium
Temporal Trends in Survival to Adulthood Among Patients Born With Congenital Heart Disease From 1970 to 1992 in Belgium
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DOI：
10.1161/circulationaha.110.946343
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发表时间：
2010-11-30
期刊：
影响因子：
37.8
通讯作者：
Gewillig, Marc
中科院分区：
文献类型：
--
作者：
Moons, Philip;Bovijn, Lore;Gewillig, Marc
背景-在过去的几十年里，患有先天性心脏病（CHD）的个体的预期寿命显著增加。然而，准确的估计生存到成年的冠心病患者是稀缺的。我们调查了1990年至1992年出生的CHD患者存活至成年的比例。我们还比较了他们的生存与出生在较早的时代，冠心病患者和评估生存的心脏defect.Methods和结果的类型的功能，我们回顾了CHD程序的行政和临床数据库在大学医院鲁汶（鲁汶，比利时）和分析的记录7497冠心病患者出生于1970年至1992年。1990年至1992年出生的患者18岁生存率为88.6%（95%可信区间[CI]，86.3%至90.5%），显著高于前几十年出生的患者（P
Background-Over the past decades, the life expectancy of individuals with congenital heart disease (CHD) has increased significantly. However, precise estimates for survival to adulthood are scarce for patients with CHD. We investigated the proportion of CHD patients born between 1990 and 1992 who survived into adulthood. We also compared their survival with that of CHD patients born in earlier eras and evaluated survival as a function of the type of heart defect.Methods and Results-We reviewed the CHD program administrative and clinical database at the University Hospitals Leuven (Leuven, Belgium) and analyzed the records of 7497 CHD patients born from 1970 to 1992. Survival to 18 years of age in patients born between 1990 and 1992 was 88.6% (95% confidence interval [CI], 86.3% to 90.5%), which was significantly greater than that of patients born in previous decades (P