Quantitative assessment of radiodermatitis through a non-invasive objective procedure in patients with breast cancer
Quantitative assessment of radiodermatitis through a non-invasive objective procedure in patients with breast cancer
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DOI：
10.3892/mco.2019.1948
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发表时间：
2020-01-01
影响因子：
1.2
通讯作者：
Osanai, Tomohiro
中科院分区：
文献类型：
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作者：
Kitajima, Maiko;Mikami, Kasumi;Osanai, Tomohiro
为了给接受过放射治疗的乳腺癌患者提供有关皮肤自我护理的建议，有必要对皮肤状况进行评估。在本研究中，使用客观评估工具对患者的急性和慢性放射性皮炎进行了分析。对18例乳腺癌放疗妇女在放疗前和放疗后6个月进行了皮肤表面温度(SST)、皮肤表面水合程度(HL)、黑色素强度(MI)和红斑强度(EI)的测定。此外，使用不良事件通用术语标准(CTCAE)评估皮肤状况。照射部位的EI和MI水平在放射治疗结束时达到峰值，并在6个月时下降到基线水平。与之相比，放射治疗期间受照部位SST水平升高(P
Assessment of skin condition is necessary for providing advice regarding skin self-care to patients with breast cancer who have undergone radiation therapy. Acute and chronic phases of radiodermatitis were analyzed in patients using objective assessment tools in the present study. A total of 18 women who received radiation therapy for breast cancer were enrolled in the present study and their skin surface temperature (SST), hydration level of the skin surface (HL), melanin intensity (MI) and erythema intensity (EI) were measured prior to radiation therapy and six months thereafter. Furthermore, skin condition was assessed using the Common Terminology Criteria for Adverse Events (CTCAE). EI and MI levels at the irradiated site peaked upon the completion of radiation therapy and declined to baseline at 6 months. In contrast, SST levels were elevated at the irradiated site during radiation therapy (P