Dynamic-Ventilatory Digital Radiography in Air Flow Limitation: A Change in Lung Area Reflects Air Trapping
Dynamic-Ventilatory Digital Radiography in Air Flow Limitation: A Change in Lung Area Reflects Air Trapping
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DOI：
10.1159/000506881
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发表时间：
2020-05-01
期刊：
影响因子：
3.7
通讯作者：
Tanaka, Rie
中科院分区：
文献类型：
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作者：
Ohkura, Noriyuki;Kasahara, Kazuo;Tanaka, Rie
目的：本研究的目的是确定动态通气数字x线摄影（DR）在气流受限患者肺功能评估中的应用价值。方法：对118例气流受限患者（术前肺癌72例，慢性阻塞性肺疾病（COPD） 35例，哮喘6例，哮喘-COPD重叠综合征5例）进行动态通气dr评估，指导患者缓慢最大呼气。使用动态平板成像系统以每秒15帧的速度捕获连续的胸部x线图像。分析肺面积与呼吸运动引起的肺面积变化率与肺功能之间的关系。结果：从最大吸气到最大呼气的肺面积变化率（Rs比）与气流受限患者的RV/TLC比（r = 0.48, p < 0.01）和预测FEV1的百分比（r = -0.33, p < 0.01）相关。Rs比值也以fev1依赖的方式下降。结论：动态DR评价呼吸运动引起的肺面积变化率反映了空气捕获。动态DR是COPD患者肺功能综合评估的潜在工具。
Objective: The aim of this study was to determine the utility of dynamic-ventilatory digital radiography (DR) for pulmonary function assessment in patients with airflow limitation. Methods: One hundred and eighteen patients with airflow limitation (72 patients with lung cancer before surgery, 35 patients with chronic obstructive pulmonary disease [COPD], 6 patients with asthma, and 5 patients with asthma-COPD overlap syndrome) were assessed with dynamic-ventilatory DR. The patients were instructed to inhale and exhale slowly and maximally. Sequential chest X-ray images were captured in 15 frames per second using a dynamic flat-panel imaging system. The relationship between the lung area and the rate of change in the lung area due to respiratory motion with respect to pulmonary function was analyzed. Results: The rate of change in the lung area from maximum inspiration to maximum expiration (Rs ratio) was associated with the RV/TLC ratio (r = 0.48, p < 0.01) and the percentage of the predicted FEV1 (r = -0.33, p < 0.01) in patients with airflow limitations. The Rs ratio also decreased in an FEV1-dependent manner. Conclusion: The rate of change in the lung area due to respiratory motion evaluated with dynamic DR reflects air trapping. Dynamic DR is a potential tool for the comprehensive assessment of pulmonary function in patients with COPD.