Malignant lymphoma of the oral cavity: clinicopathologic analysis of 20 cases.
Malignant lymphoma of the oral cavity: clinicopathologic analysis of 20 cases.
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口腔恶性淋巴瘤20例临床病理分析。
DOI：
10.1111/j.1600-0714.1987.tb00669.x
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
K. Aozasa
中科院分区：
文献类型：
--
作者：
Y. Fukuda;T. Ishida;M. Fujimoto;T. Ueda;K. Aozasa
根据最近的组织学分类，对 20 例口腔恶性淋巴瘤（ML）进行了回顾。其中男性 12 例，女性 8 例，年龄范围 11-80 岁（中位年龄 51 岁）。百分之八十的患者处于 IE 和 IIE 期。组织学上，15例（75%）为普通非霍奇金淋巴瘤（NHL），以弥漫性大细胞型最为常见。其余5例无法通过普通NHL分类方案定义，分别被指定为口腔恶性组织细胞增多症（3例）和外周T细胞淋巴瘤（2例）。无滤泡性淋巴瘤病例。目前的病例包括 45% 的高级别恶性肿瘤、40% 的中级别恶性肿瘤和 15% 的低级别恶性肿瘤。后续研究表明，死亡阶段、组织学分类和有丝分裂频率与生存率密切相关。
Twenty cases of malignant lymphomas (ML) of the oral cavity were reviewed in the light of recent histologic classification. They occurred in 12 male and 8 female patients, with the age range of 11-80 years (median 51 years of age). Eighty percent of patients were stages IE and IIE. Histologically, 15 cases (75%) were ordinary non-Hodgkin's lymphoma (NHL) with diffuse large cell type being the most common. The remaining 5 cases, undefinable by classification scheme for ordinary NHL, were designated as malignant histiocytosis of the oral cavity (3 cases) and peripheral T-cell lymphoma (2 cases), respectively. There were no cases of follicular lymphoma. The present cases comprised 45% of high grade, 40% of intermediate grade, and 15% of low grade malignancy. A follow-up study showed that the stage of diseage, histologic classification, and frequency of mitosis correlated well with survival.