Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula
Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula
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DOI：
10.1016/j.phytochem.2008.04.021
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发表时间：
2008-07-01
期刊：
影响因子：
3.8
通讯作者：
Ashootosh, Tripathi
中科院分区：
文献类型：
--
作者：
Tan, Lik Tong;Chang, Ying Yan;Ashootosh, Tripathi
Besarhanamides A(1)和B(2)是从新加坡汉图岛收集的海洋蓝藻Lyngbya majuscula中纯化的脂肪酸酰胺。这些次级代谢物的结构测定是使用广泛的二维核磁共振光谱数据以及包括Marfey方法在内的化学操作进行的。此外，贝沙汉酰胺A在13 μ M的盐水对虾毒性生物测定中表现出中等毒性，LD（50）。(C) 2008 Elsevier Ltd版权所有。
Besarhanamides A(1) and B(2) are fatty acid amides purified from the marine cyanobacterium, Lyngbya majuscula, collected from Pulau Hantu, Singapore. The structure determination of these secondary metabolites was carried out using extensive 2D NMR spectral data as well as chemical manipulations including the Marfey's method. In addition, besarhanamide A exhibited moderate toxicity with LD(50) at 13 mu M in the brine shrimp toxicity bioassay. (C) 2008 Elsevier Ltd. All rights reserved.