Combined 5-minute double-echo in steady-state with separated echoes and 2-minute proton-density-weighted 2D FSE sequence for comprehensive whole-joint knee MRI assessment
Combined 5-minute double-echo in steady-state with separated echoes and 2-minute proton-density-weighted 2D FSE sequence for comprehensive whole-joint knee MRI assessment
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DOI：
10.1002/jmri.26582
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发表时间：
2019-06-01
影响因子：
4.4
通讯作者：
Hargreaves, Brian A.
中科院分区：
文献类型：
--
作者：
Chaudhari, Akshay S.;Stevens, Kathryn J.;Hargreaves, Brian A.
背景临床膝关节MRI检查需要15分钟以上的扫描时间。目的/假设比较5分钟双回波稳态(DESS)序列和常规临床膝关节MRI检查方法所显示的膝关节异常的影像表现。第二个目标是比较5分钟的DESS和2分钟的冠状质子密度脂肪饱和(PDF)序列所描绘的膝关节异常的成像外观。研究类型展望主题36名连续的患者(19名男性)进行了常规的膝关节MRI。场强/序列在3T时DESS和PDF。评估五位肌肉骨骼放射科医生使用DESS、DESS+PDF和常规成像方案评估了所有图像是否存在膝关节内部紊乱，以及他们相关的诊断读数的可信度。统计测试在阳性和阴性百分比一致性(PPA和NPA，NPA，DESS和DESS+PDF与常规方案相比的95%可信区间(CI)被计算并使用精确的McNemar检验进行检验。使用精确对称性检验来检验DESS或DESS+PDF具有与DESS+Conv相同置信度的观察的百分比。结果DESS的PPA为90%(88-92%CI)，NPA为99%(99-99%CI)。与DESS(P<；0.001)相比，DESS+PDF的PPA增加了99%(95-99%CI)，NPA增加了100%(99-100%CI)。在94%的诊断结果中，DESS与DESS+Conv具有相同的诊断置信度，而在99%的发现中，DESS+PDF具有相同的诊断置信度(P<；0.001)。所有读者对三种方案的符合率均为中等(Krippendorff‘s Alpha为47%-48%)。数据结论1)5分钟回声分离的3D-DESS和2)5分钟的3D-DESS和2分钟的冠状PDF序列对膝关节异常的显示类似于常规的临床膝关节MRI方案，这可能是一种有前景的简化膝关节MRI技术。证据级别：2技术效力：阶段2 J.马根。雷森。想象2018年。
BackgroundClinical knee MRI protocols require upwards of 15 minutes of scan time.Purpose/HypothesisTo compare the imaging appearance of knee abnormalities depicted with a 5-minute 3D double-echo in steady-state (DESS) sequence with separate echo images, with that of a routine clinical knee MRI protocol. A secondary goal was to compare the imaging appearance of knee abnormalities depicted with 5-minute DESS paired with a 2-minute coronal proton-density fat-saturated (PDFS) sequence.Study TypeProspective.SubjectsThirty-six consecutive patients (19 male) referred for a routine knee MRI.Field Strength/SequencesDESS and PDFS at 3T.AssessmentFive musculoskeletal radiologists evaluated all images for the presence of internal knee derangement using DESS, DESS+PDFS, and the conventional imaging protocol, and their associated diagnostic confidence of the reading.Statistical TestsDifferences in positive and negative percent agreement (PPA and NPA, respectively) and 95% confidence intervals (CIs) for DESS and DESS+PDFS compared with the conventional protocol were calculated and tested using exact McNemar tests. The percentage of observations where DESS or DESS+PDFS had equivalent confidence ratings to DESS+Conv were tested with exact symmetry tests. Interreader agreement was calculated using Krippendorff's alpha.ResultsDESS had a PPA of 90% (88-92% CI) and NPA of 99% (99-99% CI). DESS+PDFS had increased PPA of 99% (95-99% CI) and NPA of 100% (99-100% CI) compared with DESS (both P < 0.001). DESS had equivalent diagnostic confidence to DESS+Conv in 94% of findings, whereas DESS+PDFS had equivalent diagnostic confidence in 99% of findings (both P < 0.001). All readers had moderate concordance for all three protocols (Krippendorff's alpha 47-48%).Data ConclusionBoth 1) 5-minute 3D-DESS with separated echoes and 2) 5-minute 3D-DESS paired with a 2-minute coronal PDFS sequence depicted knee abnormalities similarly to a routine clinical knee MRI protocol, which may be a promising technique for abbreviated knee MRI. Level of Evidence: 2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018.